Neuroepidemiology

Original Paper

Campylobacter jejuni Infection and Guillain-Barré Syndrome: A Case-Control Study

Emilia-Romagna Study Group on Clinical and Epidemiological Problems in Neurology E.1

Keywords: Guillain-Barré syndromeCampylobacter jejuniCase-control study

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Neuroepidemiology 1998;17:296–302
https://doi.org/10.1159/000026183

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: October 23, 1998
Issue release date: November – December

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 1

ISSN: 0251-5350 (Print)
eISSN: 1423-0208 (Online)

For additional information: https://www.karger.com/NED

Abstract

We performed a case-control study to investigate the association between Campylobacter jejuni (CJ) infection and Guillain-Barré syndrome (GBS) or Miller-Fisher syndrome. We compared 60 cases with 109 hospital controls matched for age, gender, hospital and geographical location.To diagnose the CJ infection, we considered the association between serologic positivity for CJ and a previous diarrheal illness within 3 months of inclusion in the study. Fifteen percent of cases versus 5% of hospital controls had CJ infection (p < 0.003, OR = 3.96, 95% CI: 1.08–17.85). However, CJ infection was related to GBS only if it occurred during the previous month (p < 0.001, OR = 7.29, 95% CI: 1.43–71.28). No statistical differences were found between the cases who were positive for CJ infection and those who were negative for CJ infection when studied by stepwise multivariate logistic regression for age, gender, clinical and electrophysiological features and outcome. Recent CJ infection may be a risk factor for GBS.



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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Published online: October 23, 1998
Issue release date: November – December

Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 1

ISSN: 0251-5350 (Print)
eISSN: 1423-0208 (Online)

For additional information: https://www.karger.com/NED

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1998, Vol.17, No. 6

November – December

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