Neuropsychobiology

Biological PsychiatryMain Editor: J. Mendlewicz (Brussels)Original Paper

Gender-Related Seasonality of Human Platelet Phenolsulfotransferase Activity

Marazziti D. · Palego L. · Rossi A. · Cassano G.B.

Author affiliations

Dipartimento di Psichiatria, Neurobiologia, Farmacologia e Biotecnologie, Università di Pisa, Italia

Keywords: SeasonalityGenderPhenolsulfotransferaseHuman plateletsCatecholaminesPhenolic compounds

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Neuropsychobiology 1998;38:1–5
https://doi.org/10.1159/000026509

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Article / Publication Details

First-Page Preview
Abstract of Biological PsychiatryMain Editor: J. Mendlewicz (Brussels)Original Paper

Published online: August 14, 1998
Issue release date: August 1998

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0

ISSN: 0302-282X (Print)
eISSN: 1423-0224 (Online)

For additional information: https://www.karger.com/NPS

Abstract

This study focused on the investigation of the possible effect of gender and season on the activity of the thermolabile and thermostable forms of platelet phenolsulfotransferase (PST) in a group of 23 healthy, drug-free volunteers of both sexes. The results showed a different seasonal profile of PST activity in men and women: in men, PST seasonal rhythms revealed a shallow profile with higher values in both the spring and summer than in the autumn. Conversely, in women, the PST seasonality showed a profile consisting overall of a main peak in the summer. Also, significant gender-dependent correlations were found between the photoperiod length and PST values. Our findings should stimulate further investigation into gender-dependent molecular mechanisms underlying the regulation of the metabolism of endogenous and xenobiotic agents, such as monoamines and phenols, which are the substrates of PST.



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Article / Publication Details

First-Page Preview
Abstract of Biological PsychiatryMain Editor: J. Mendlewicz (Brussels)Original Paper

Published online: August 14, 1998
Issue release date: August 1998

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0

ISSN: 0302-282X (Print)
eISSN: 1423-0224 (Online)

For additional information: https://www.karger.com/NPS

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1998, Vol.38, No. 1

August 1998

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