Ophthalmic Research
Original Paper
Effect of Aspirin and Vitamin E on Phase Separation in Calf Lens HomogenateEccarius S.a · Clark J.I.b bDepartment of Biological Structure, University of Washington, School of Medicine, Seattle, Wash., andaUniversity of South Dakota, School of Medicine, Vermillion, S. Dak., USA
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Article / Publication Details
Received: November 15, 1985
Accepted: August 27, 1986
Published online: December 04, 2009
Issue release date: 1987
Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0
ISSN: 0030-3747 (Print)
eISSN: 1423-0259 (Online)
For additional information: https://www.karger.com/ORE
Abstract
Vitamin E (d-alpha-tocopherol) and aspirin were evaluated for their effects on the phase separation temperature, Tc, of calf lens cytoplasm. Vitamin E and aspirin were added to nuclear homogenate and the change in Tc was measured. Aspirin had no measurable effect on Tc. Vitamin E lowered Tc at a rate of-22°C M––1 1––1. The results suggest that the effects of aspirin on cataract are unrelated to phase separation and that vitamin E may act on the phase separation in precataractous lens cells.
© 1987 S. Karger AG, Basel
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Article / Publication Details
Received: November 15, 1985
Accepted: August 27, 1986
Published online: December 04, 2009
Issue release date: 1987
Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0
ISSN: 0030-3747 (Print)
eISSN: 1423-0259 (Online)
For additional information: https://www.karger.com/ORE
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