Ophthalmic Research
Original Paper
A Model to Induce Scattered Cell Damage in the Corneal EndotheliumLin C.-P.a · Böhnke M.b · Draeger J.baDepartment of Ophthalmology, Kaohsiung Medical College, Kaohsiung, Taiwan, ROC; bHamburg University Eye Clinic, Hamburg, FRG
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Article / Publication Details
Received: October 08, 1987
Accepted: June 01, 1988
Published online: December 10, 2009
Issue release date: 1989
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0
ISSN: 0030-3747 (Print)
eISSN: 1423-0259 (Online)
For additional information: https://www.karger.com/ORE
Abstract
A model to induce scattered cell damage in the corneal endothelium was set up by shaking a pig cornea in a glass bottle with 0.18 % NaCl. Disseminated endothelial-cell losses, whose amounts correlated with the durations of treatment, were observed in the corneas which were shaken for less than 8 min. Following organ culturing for 1 week, most of the corneas still possessed intact endothelia which means that even after the treatment the endothelium still keeps a normal regenerative ability. With this method of design, a good model is provided to study the regeneration of the corneal endothelium.
© 1989 S. Karger AG, Basel
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Article / Publication Details
Received: October 08, 1987
Accepted: June 01, 1988
Published online: December 10, 2009
Issue release date: 1989
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0
ISSN: 0030-3747 (Print)
eISSN: 1423-0259 (Online)
For additional information: https://www.karger.com/ORE
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