Ophthalmic Research
Original Paper
Dopaminergic Interplexif orm Cells in the Retina of Pigmented and Hypopigmented Quails (Coturnix coturnix japonica)Dkhissi O.a · Dalil-Thiney N.a · Versaux-Botteri C.a,b · Chanut E.c · Repérant J.a,d · Nguyen-Legros J.baLaboratoire d’Anatomie Comparée, Museum National d’Histoire Naturelle; bLaboratoire de Neurocytologie Oculaire, INSERM U-86, Paris; cLaboratoire de Pharmacologie, Faculté de Pharmacie, Université de Paris Sud, Châtenay-Malabry; dINSERM U-106, Hôpital de La Salpêtrière, Paris, France
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Article / Publication Details
Received: November 30, 1992
Accepted: February 23, 1993
Published online: December 11, 2009
Issue release date: 1993
Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 0
ISSN: 0030-3747 (Print)
eISSN: 1423-0259 (Online)
For additional information: https://www.karger.com/ORE
Abstract
Interplexiform cells (IPCs) have not been previously described as a component of the population of tyrosine hydroxylase (TH) immunoreactive (presumably dopaminergic) cells in the avian retina. In this study, carried out in both pigmented and imperfect albino mutant quails (Coturnix coturnix japonica), we initially describe TH immunoreactive cells in the inner nuclear layer whose internal dendritic arborization extends into strata 1 3 and 4/5 of the inner plexiform layer. Then, we describe ascending processes arising from the somata or proximal dendrites of these cells. These sclerally directed processes (100-1,000 μm long) run across the inner nuclear layer to terminate within the outer plexiform layer, sometimes even reaching the outer nuclear layer. Hence, the cells bearing such processes correspond well with the definition of IPCs. The number of scleral processes is higher in mutant (48 ± 19/retina) than in normal (12 ± 10/retina) quails and are distributed throughout the retina except the area surrounding the pecten. Comparison of biochemical assays for dopamine in the two strains reveals a significantly higher dopamine content in the mutant quails which could be related to its increased number of dopaminergic IPC processes.
© 1993 S. Karger AG, Basel
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Article / Publication Details
Received: November 30, 1992
Accepted: February 23, 1993
Published online: December 11, 2009
Issue release date: 1993
Number of Print Pages: 9
Number of Figures: 0
Number of Tables: 0
ISSN: 0030-3747 (Print)
eISSN: 1423-0259 (Online)
For additional information: https://www.karger.com/ORE
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