Ophthalmic Research
Calcium Distribution in the Human Eye LensVrensen G.F.J.M. · de Wolf A.Department of Morphology, The Netherlands Ophthalmic Research Institute, Amsterdam, The Netherlands
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Article / Publication Details
Published online: December 11, 2009
Issue release date: 1996
Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0
ISSN: 0030-3747 (Print)
eISSN: 1423-0259 (Online)
For additional information: https://www.karger.com/ORE
Abstract
The distribution of calcium in the human eye lens was investigated using the oxalate-pyroantimonate technique. In epithelial cells and superficial cortical fibers calcium is sequestered and tightly bound to proteins in the endoplasmic reticulum, nuclear envelope, Golgi cisterns and mitochondria. In intermediate fibers these cell organelles are broken down and the liberated calcium is ionically bound to the phospholipids at the extracellular side of the fiber-limiting membrane. It is argued that calcium is probably additionally bound to β-crystallin. This site-specific variation in calcium storage might explain the deeper cortical localization of early focal dot opacities and retrodots.
© 1996 S. Karger AG, Basel
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Article / Publication Details
Published online: December 11, 2009
Issue release date: 1996
Number of Print Pages: 8
Number of Figures: 0
Number of Tables: 0
ISSN: 0030-3747 (Print)
eISSN: 1423-0259 (Online)
For additional information: https://www.karger.com/ORE
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