Acta Haematologica
Brief Communication
Erythropoietin and Cyclophosphamide Combination Treatment Additively Enhances Antibody Production in MiceLifshitz L.a · Berger A.a · Mittelman M.b · Neumann D.aaDepartment of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel Aviv University, bDepartment of Medicine, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
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Article / Publication Details
Received: August 18, 2009
Accepted: October 12, 2009
Published online: December 23, 2009
Issue release date: February 2010
Number of Print Pages: 3
Number of Figures: 1
Number of Tables: 0
ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)
For additional information: https://www.karger.com/AHA
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References
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- Jelkmann W, Bohlius J, Hallek M, Sytkowski AJ: The erythropoietin receptor in normal and cancer tissues. Crit Rev Oncol Hematol 2008;67:39–61.
- Mittelman M, Zeidman A, Fradin Z, Magazanik A, Lewinski UH, Cohen A: Recombinant human erythropoietin in the treatment of multiple myeloma-associated anemia. Acta Haematol 1997;98:204–210.
- Mittelman M, Neumann D, Peled A, Kanter P, Haran-Ghera N: Erythropoietin induces tumor regression and antitumor immune responses in murine myeloma models. Proc Natl Acad Sci USA 2001;98:5181–5186.
- Prutchi-Sagiv S, Golishevsky N, Oster HS, Katz O, Cohen A, Naparstek E, Neumann D, Mittelman M: Erythropoietin treatment in advanced multiple myeloma is associated with improved immunological functions: could it be beneficial in early disease? Br J Haematol 2006;135:660–672.
- Katz O, Gil L, Lifshitz L, Prutchi-Sagiv S, Gassmann M, Mittelman M, Neumann D: Erythropoietin enhances immune responses in mice. Eur J Immunol 2007;37:1584–1593.
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- Lutsiak ME, Semnani RT, De Pascalis R, Kashmiri SV, Schlom J, Sabzevari H: Inhibition of CD4(+)25+ T regulatory cell function implicated in enhanced immune response by low-dose cyclophosphamide. Blood 2005;105:2862–2868.
- Lifshitz L, Prutchi-Sagiv S, Avneon M, Gassmann M, Mittelman M, Neumann D: Non-erythroid activities of erythropoietin: functional effects on murine dendritic cells. Mol Immunol 2009;46:713–721.
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Article / Publication Details
Received: August 18, 2009
Accepted: October 12, 2009
Published online: December 23, 2009
Issue release date: February 2010
Number of Print Pages: 3
Number of Figures: 1
Number of Tables: 0
ISSN: 0001-5792 (Print)
eISSN: 1421-9662 (Online)
For additional information: https://www.karger.com/AHA
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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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