Urologia Internationalis
Zur Frage des histologischen Aufbaus des pelviureteralen Segmentes bei kongenitaler HarnstauungsniereFladerer H. · Hubmer G.Institut für Pathologische Anatomie der Universität Graz (Vorstand: Prof. M. Ratzenhofer) und Departement für Urologie (Leiter: Prof. G. Hubmer), Universitätsklinik für Chirurgie (Vorstand: Prof. J. Kraft-Kinz), Graz
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Article / Publication Details
Published online: January 27, 2010
Issue release date: 1975
Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0
ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)
For additional information: https://www.karger.com/UIN
Abstract
Histological investigation of ureteropelvic junction (UPJ) specimens of 21 patients with congenital hydronephrosis revealed in 7 instances pathological changes, which might be responsible for the obstruction. In 15 cases a significant increase of collagenous tissue within the UPJ, along with a relative deficiency of monocytes was noted. Each of the smooth muscle fibers was surrounded by fibrous tissue, which caused interruption of the ‘nexus’ function and therefore loss of muscle contractions. The inability of normal muscle contractions within the UPJ might be a contributing factor to the pathogenesis of congenital hydronephrosis.
© 1975 S. Karger AG, Basel
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Article / Publication Details
Published online: January 27, 2010
Issue release date: 1975
Number of Print Pages: 7
Number of Figures: 0
Number of Tables: 0
ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)
For additional information: https://www.karger.com/UIN
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