Urologia Internationalis
Original Paper
Calcium Oxalate Retention in Subjects with CrystalluriaBurns J.R.a · Finlayson B.b · Gauthier J.aaDivision of Urology, Department of Surgery, University of Alabama in Birmingham, Birmingham, Ala., USA; bDivision of Urology, Department of Surgery, University of Florida, Gainesville, Fla., USA
Keywords: Calcium oxalateCrystalluriaCalculi |
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Article / Publication Details
Received: June 20, 1983
Accepted: June 23, 1983
Published online: January 29, 2010
Issue release date: 1984
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0
ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)
For additional information: https://www.karger.com/UIN
Abstract
Calcium oxalate retention was studied in non-stone-forming volunteers. All subjects were placed on a constant diet for 5 days. After the oral administration of 10 µCi of [14C]-oxalic acid, the pattern of urinary oxalate excretion was followed for 48 h. Each subject was then given 10 µCi of [14C]-oxalic acid mixed with sufficient sodium oxalate (7.5 mg/kg body weight) to induce calcium oxalate crystalluria. Urinary oxalate excretion was then recorded for 48 h. After the administration of labeled oxalic acid (without additional sodium oxalate), 76.6 ± 5.9% of the total recovered dose was excreted by 4 h. When the labeled oxalic acid was mixed with a sodium oxalate load, 62.4 ± 8.8 % was excreted by 4 h (p < 0.01). Induction of calcium oxalate crystalluria results in the retention of oxalate in the kidney. The degree of retention varies among individuals. Differences in particle retention may help explain the differences between stone formers and non-stone formers
© 1984 S. Karger AG, Basel
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Article / Publication Details
Received: June 20, 1983
Accepted: June 23, 1983
Published online: January 29, 2010
Issue release date: 1984
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0
ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)
For additional information: https://www.karger.com/UIN
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