Importance of Growth for Health and Development

65th Nestlé Nutrition Institute Workshop, Pediatric Program, Kuala Lumpur, March 2009

Editor(s): Lucas, A. (London)
Makrides, M. (Adelaide, SA)
Ziegler, E.E. (Iowa City, IA)

Growth and Neurological Development

Benefits and Harms of Iron Supplementation in Iron-Deficient and Iron-Sufficient Children

Domellöf M.

Author affiliations

Department of Clinical Sciences, Pediatrics, Umeå University Hospital, Umeå, Sweden

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Lucas A, Makrides M, Ziegler EE (eds): Importance of Growth for Health and Development. Nestlé Nutr Inst Workshop Ser Pediatr Program, vol 65, pp 153–165, Nestec Ltd., Vevey/S. Karger AG, Basel, © 2010
https://doi.org/10.1159/000281159

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Article / Publication Details

First-Page Preview
Abstract of Growth and Neurological Development

Published online: February 01, 2010
Cover Date: 2010

Number of Print Pages: 13
Number of Figures: 0
Number of Tables: 0

ISBN: 978-3-8055-9304-5 (Print)
eISBN: 978-3-8055-9305-2 (Online)

Abstract

Due to high iron requirements, young children are at risk for iron deficiency anemia. Iron supplements are therefore often recommended, especially since iron deficiency anemia in children is associated with poor neurodevelopment. However, in contrast to most other nutrients, excess iron cannot be excreted by the human body and it has recently been suggested that excessive iron supplementation of young children may have adverse effects on growth, risk of infections, and even on cognitive development. Recent studies support that iron supplements are beneficial in iron-deficient children but there is a risk of adverse effects in those who are iron replete. In populations with a low prevalence of iron deficiency, general supplementation should therefore be avoided. Iron-fortified foods can still be generally recommended since they seem to be safer than medicinal iron supplements, but the level of iron fortification should be limited. General iron supplementation is recommended in areas with a high prevalence of iron deficiency, with the exception of malarious areas where a cautious supplementation approach needs to be adopted, based either on screening or a combination of iron supplements and infection control measures. More studies are urgently needed to better determine the risks and benefits of iron supplementation and iron-fortified foods given to iron-deficient and iron-sufficient children.

© 2010 S. Karger AG, Basel



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References

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Article / Publication Details

First-Page Preview
Abstract of Growth and Neurological Development

Published online: February 01, 2010
Cover Date: 2010

Number of Print Pages: 13
Number of Figures: 0
Number of Tables: 0

ISBN: 978-3-8055-9304-5 (Print)
eISBN: 978-3-8055-9305-2 (Online)

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