Urologia Internationalis
Original Paper
Effects of the pH and the Urine Infected by Escherichia coli and Proteus mirabilis on Chromic Catgut, Polyglycolic Acid and Polyglactin 910: Study in vitroHering F.L.O. · Rosenberg D. · Chade J.Department of Surgery Technique and Experimental Surgery, ‘Paulista Medical School’ and Sírio-Libanês’ Hospital, São Paulo, Brazil
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Article / Publication Details
Received: November 08, 1988
Accepted: January 03, 1989
Published online: January 29, 2010
Issue release date: 1989
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0
ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)
For additional information: https://www.karger.com/UIN
Abstract
In order to study the effects of the pH and the urine infected by Escherichia coli and Proteus mirabilis on chromic catgut, polyglycolic acid (PGA) and polyglactin 910 (P910), we divided the experiment into three steps. In the first step, the behavior of suture material immersed in sterile urine, urine infected by E. coli and urine infected by P. mirabilis and in culture environment infected by P. mirabilis was studied. The physical features were observed continuously up to the 6th day. In the second step, every element of the urea-splitting reaction was isolatedly studied, without the presence of bacterial agents. And in the last step, that reaction was mimetized in sterile environment and in environments with acid and alkaline pH. While the chromic catgut was kept integral in all the environments, the PGA and the P910 dissolved in urine infected by Proteus, which was caused by the ammonia resulting from the urea-splitting reaction. This dissolution was also observed in sterile environment (mimetization of the urea-splitting reaction by urease, with no Proteus). The destruction of the sutures was not influenced by the pH variance.
© 1989 S. Karger AG, Basel
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Article / Publication Details
Received: November 08, 1988
Accepted: January 03, 1989
Published online: January 29, 2010
Issue release date: 1989
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0
ISSN: 0042-1138 (Print)
eISSN: 1423-0399 (Online)
For additional information: https://www.karger.com/UIN
Copyright / Drug Dosage / Disclaimer
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