Pediatric Neurosurgery
Case Report
Familial Intracranial Arteriovenous MalformationsCase Repo rt and Review of the Literature Departments of Neurosurgery, Children’s Hospital, and Massachusetts General Hospital, Boston, Mass., and Mount Sinai Hospital, New York, N.Y., USA
|
|
Log in to MyKarger to check if you already have access to this content.
KAB
Buy a Karger Article Bundle (KAB) and profit from a discount!
If you would like to redeem your KAB credit, please log in.
Save over 20% compared to the individual article price.
Article / Publication Details
Published online: January 07, 1999
Issue release date: October 1998
Number of Print Pages: 6
Number of Figures: 7
Number of Tables: 1
ISSN: 1016-2291 (Print)
eISSN: 1423-0305 (Online)
For additional information: https://www.karger.com/PNE
Abstract
Familial intracranial arteriovenous malformations (AVMs) are rare. We describe a father and son both presenting in childhood with cerebral AVMs. Both patients underwent successful surgical extirpation of the AVM. Familial AVMs present at a young age and tend to be multiple, as was the case in one of our patients. Imaging of asymptomatic family members may detect previously undiagnosed AVMs, and we recommend screening of the relatives of patients with a strong family history of such lesions.
Related Articles:
References
- Zabramski JM, Wascher TM, Spetzler RF, Johnson B, Golfinos J, Drayer BP, Brown B, Rigamonti D, Brown G: The natural history of familial cavernous malformations: results of an ongoing study. J Neurosurg 1994;80:422–432.
-
Kidd HA, Cumings JN: Cerebral angiomata in an icelandic family. Lancet 1947;i:747–748.
-
Griepentrog v. F: Über Erblichkeit bei Angiomen des Gehirns. Nervenarzt 1951;304–305.
- Laing JW, Smith RR: Intracranial arteriovenous malformations in sisters: A case report. J Miss State Med Assoc 1974;15:203–206.
- Stoll W, Wolfram A: Intrakranielle familiäre Gefässanomalie aus hals-nasen-ohrenärztlicher und neurologischer Sicht. HNO 1977;25:7–12.
- Barre RG, Suter CG, Rosenblum WI: Familial vascular malformation or chance occurrence? Case report of two affected family members. Neurology 1978;28:98–100.
- Snead OC III, Acker JD, Morawetz R: Familial arteriovenous malformation. Ann Neurol 1979;5:585–587.
- Aberfeld DC, Rao KR: Familial arteriovenous malformation of the brain. Neurology 1981;31:184–186.
-
Yamamoto S, Ando K, Suzuki Y, Kaho M, Arneya T, Tsuda T: Cerebral arteriovenous malformation occurring in two patients of mother-daughter combination. Rinsho Shinkeigaku 1983;2:908.
-
Boyd MC, Steinbok P, Paty DW: Familial arteriovenous malformations. Report of four cases in one family. J Neurosurg 1985;62:596–599.
- Morita T, Iwai T, Takada M, Miwa Y, Funakoshi T, Sakai N, Yamada H: Familial occurrence of intracranial arteriovenous malformation. No Shinkei Geka 1985;13:181–186.
- Zellem RT, Buchheit WA: Multiple intracranial arteriovenous malformations: Case report. Neurosurgery 1985;17:88–93.
- Bucci MN, Chandler WF, Gebarski SS, McKeever PE: Multiple progressive familial thrombosed arteriovenous malformations. Neurosurgery 1986;19:401–404.
- Allard JC, Hochberg FH, Franklin PD, Carter AP: Magnetic resonance imaging in a family with hereditary cerebral arteriovenous malformations. Arch Neurol 1989;46:184–187.
- Yokoyama K, Yoshitaka A, Takatsugu M, Takada M, Ando T, Sakai N, Yamada H, Iwata H: Familial occurrence of arteriovenous malformation of the brain. J Neurosurg 1991;74:585–589.
- Goto S, Abe M, Tsuji T, Tabuchi K: Familial arteriovenous malformations of the brain. Two case reports. Neurol Med Chir (Tokyo) 1994;34:221–224.
- Brilli RJ, Sacchetti A, Neff S: Familial arteriovenous malformations in children. Pediatr Emerg Care 1995;11:376–378.
- Sobel D, Norman D: CNS manifestations of hereditary hemorrhagic telangiectasia. AJNR Am J Neuroradiol 1984;5:569–573.
- Willinsky RA, Lasjaunias P, Terbrugge K, Burrows P: Multiple cerebral arteriovenous malformations. Review of our experience from 203 patients with cerebral vascular lesions. Neuroradiology 1990;32:207–210.
- Putman CM, Chaloupka JC, Fulbright RK, Awad IA, White RI Jr, Fayad PB: Exceptional multiplicity of cerebral arteriovenous malformations associated with hereditary hemorrhagic telengiectasia (Osler-Weber-Rendu syndrome). AJNR Am J Neuroradiol 1996;17:1733–1742.
- King CR, Lovrien EW, Reiss J: Central nervous system arteriovenous malformations in multiple generations of a family with hereditary hemorrhagic telangiectasia. Clin Genet 1977;12:372–381.
- Kadoya C, Momota Y, Ikegami Y, Urasaki E, Wada S, Yokota A: Central nervous system arteriovenous malformations with hereditary hemorrhagic telangiectasia: report of a family with three cases. Surg Neurol 1994;42:234–239.
- Kikuchi K, Kowada M, Sasajima H: Vascular malformations of the brain in hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber disease). Surg Neurol 1994;41:374–380.
- Kikuchi K, Kowada M, Sakomoto T, Tamakawa Y, Sakuragi S: Wyburn-Mason syndrome: Report of a rare case with computed tomography and angiographic evaluations. J Comput Tomogr 1988;12:111–115.
- Patel V, Gupta SC: Wyburn-Mason syndrome. A case report and review of the literature. Neuroradiology 1990;32:207–210.
-
Mohr JP: Neurological manifestations and factors related to therapeutic decisions; in Wilson CB, Stein BM (eds): Intracranial Arterovenous Malformations. Baltimore, Williams & Wilkins, 1984.
- Salcman M, Scholtz H, Numaguchi Y: Multiple intracerebral arteriovenous malformations: Report of three cases and review of the literature. Surg Neurol 1992;38:121–128.
Article / Publication Details
Published online: January 07, 1999
Issue release date: October 1998
Number of Print Pages: 6
Number of Figures: 7
Number of Tables: 1
ISSN: 1016-2291 (Print)
eISSN: 1423-0305 (Online)
For additional information: https://www.karger.com/PNE
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

Get Permission