Pediatric Neurosurgery
Original Paper
A Case of Cerebrospinal Fluid Eosinophilia Associated with Shunt MalfunctionTanaka T. · Ikeuchi S. · Yoshino K. · Isoshima A. · Abe T.Department of Neurosurgery, Jikei University School of Medicine, Tokyo, Japan
|
|
Log in to MyKarger to check if you already have access to this content.
KAB
Buy a Karger Article Bundle (KAB) and profit from a discount!
If you would like to redeem your KAB credit, please log in.
Save over 20% compared to the individual article price.
Article / Publication Details
Published online: March 31, 1999
Issue release date: January 1999
Number of Print Pages: 5
Number of Figures: 4
Number of Tables: 0
ISSN: 1016-2291 (Print)
eISSN: 1423-0305 (Online)
For additional information: https://www.karger.com/PNE
Abstract
A 3-month-old female patient presented with a meningomyelocele at the lumber region associated with congenital hydrocephalus. She underwent ventriculoperitoneal (V-P) shunt surgery using the Sophy system. The shunt system was replaced due to a malformation. Following replacement, the patient presented with cerebrospinal fluid (CSF) eosinophilia at the age of 8 months. The eosinophilic granulocytosis of the CSF improved dramatically following systemic prednisolone administration. CSF eosinophilia without accompanying inflammation or pyrexia in the present case may have resulted from an allergic response to a foreign material such as the silicone tube pressure valve of the Sophy system or the sutures rather than bacterial or fungal infection. Based on our results, we believe that some patients may experience CSF eosinophilia following postoperative V-P shunt due to an allergic reaction to the shunt equipment. Prompt steroid treatment can produce spontaneous regression in such cases.
Related Articles:
References
- Bosch I, Oehmichen M: Eosinophilic granulocytes in cerebrospinal fluid: Analysis of 94 cerebrospinal fluid specimens and review of the literature. J Neurol 1978;219:93–105.
- Budka H, Guseo A, Jellinger K, Mittermayer K: Intermittent meningitic reaction with severe basophilia and eosinophilia in CNS leukemia. J Neurol Sci 1976;28:459–468.
-
King DK, Lor KK, Alaya AG, Gamble JF: Eosinophilic meningitis and lymphomatous meningitis. Ann Intern Med 1975;82:228–229.
- Kuberski T: Eosinophils in the cerebrospinal fluid. Ann Intern Med 1979;91:70–75.
- Stayer DR, Bender RA: Eosinophilic meningitis complicating Hodgkin’s disease. Cancer 1977;40:406–409.
- Grabb PA, Albright AL: Intraventricular vancomycin-induced cerebrospinal fluid eosinophilia: Report of two patients. Neurosurgery 1992;30:630–635.
- Mine S, Sato A, Yamaura A, Tamachi S, Makino H, Tomioka H: Eosinophilia of the cerebrospinal fluid in a case of shunt infection: Case report. Neurosurgery 1986;19:835–836.
- Jimenez DF, Keating R, Goodrich JT: Silicone allergy in ventriculoperitoneal shunts. Childs Nerv Syst 1994;10:59–63.
- Kennedy CR, Singer HS: Eosinophilia of the cerebrospinal fluid: Late reaction to a silastic shunt. Dev Med Child Neurol 1988;30:386–390.
- Banta JV, Bonanni C, Prebluda J: Latex anaphylaxis during spinal surgery in children with myelomeningocele. Dev Med Child Neurol 1993;35:543–548.
-
Pittman T, Kiburz J, Gabriel K, Steinhardt G, Williams D, Slater J: Latex allergy in children with spina bifida. Pediatr Neurosurg 1975;22:96–100.
External Resources
- Engibous PJ, Kittle PE, Jones HL, Vance BJ: Latex allergy in patients with spina bifida. Pediatr Dent 1993;15:364–366.
- Traynelis V, Powell RG, Koss W, Schochet SS Jr, Kaufman HH: Cerebrospinal fluid eosinophilia and sterile shunt malfunction. Neurosurgery 1988;23:645–649.
- Tung H, Raffel C, McComb JG: Ventricular cerebrospinal fluid eosinophilia in children with ventriculoperitoneal shunts. J Neurosurg 1991;75:541–544.
Article / Publication Details
Published online: March 31, 1999
Issue release date: January 1999
Number of Print Pages: 5
Number of Figures: 4
Number of Tables: 0
ISSN: 1016-2291 (Print)
eISSN: 1423-0305 (Online)
For additional information: https://www.karger.com/PNE
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
Get Permission
PubMed ID
