Gynecologic and Obstetric Investigation

Original Paper

Oxytocin Augmentation in Arrest Disorders in the Presence of Thick Meconium: Influence on Neonatal Outcome

Morel M.-I.G. · Anyaegbunam A.M. · Mikhail M.S. · Legorreta A. · Whitty J.E.

Author affiliations

Albert Einstein College of Medicine, Department of Obstetrics and Gynecology, Bronx, N.Y., USA

Related Articles for ""

Gynecol Obstet Invest 1994;37:21–24

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: December 16, 1992
Accepted: May 18, 1993
Published online: March 01, 2010
Issue release date: 1994

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: https://www.karger.com/GOI

Abstract

The objective of this report was to study the effect of oxytocin augmentation in arrest disorders in the presence of thick meconium on meconium aspiration and fetal acidosis. We evaluated 3,321 singleton, term deliveries with cephalic presentation at our institution. Eight percent (253/3,321) had thick meconium in labor, and these patients comprised the study sample. Of the 253 women with thick meconium, 84 had an arrest disorder in the active phase of labor with normal fetal heart rate tracing at the time of diagnosis. Seventy-four percent (62/84) of the women with arrest were treated with oxytocin (group 1) and 26% (22/84) delivered by cesarean section without augmentation (group 2). There was a significant (p < 0.05) increase in the incidence of meconium aspiration (14.5 vs. 4.5%) and low ( < 7.20) cord arterial pH (27.8 vs. 4.5%) in patients who received oxytocin compared to those who did not. Of the women who received oxytocin, 36 delivered vaginally, and 2 neonates had meconium aspiration. The remaining 26 women had cesarean sections following oxytocin augmentation and had a significantly higher (p < 0.05) frequency of meconium aspiration (26.9 vs. 4.5%) and low cord arterial pH (38.5 vs. 4.5%) compared to women who had cesarean sections without oxytocin augmentation. The findings suggest that oxytocin augmentation in arrest disorders in the presence of thick meconium may be associated with a higher risk of meconium aspiration and low umbilical cord arterial pH.

© 1994 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: December 16, 1992
Accepted: May 18, 1993
Published online: March 01, 2010
Issue release date: 1994

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: https://www.karger.com/GOI


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