Gynecologic and Obstetric Investigation
Original Paper
The Outcome of Pregnancy in Antinuclear Antibody-Positive WomenKiuttu J. · Hartikainen A.-L. · Mäkitalo R. · Ruuska P.Department of Medical Microbiology and Department of Obstetrics and Gynecology, University of Oulu, Finland
Keywords: Antinuclear antibodiesPregnancy |
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Article / Publication Details
Received: January 18, 1993
Accepted: August 09, 1993
Published online: March 01, 2010
Issue release date: 1994
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0
ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)
For additional information: https://www.karger.com/GOI
Abstract
The significance of antinuclear antibodies (ANA) was studied in 51 ANA-positive women who had had a total of 170 pregnancies. 60 ANA-negative age-and parity-matched women with a total of 142 pregnancies served as controls. The perinatal mortality rate in the ANA-positive group was 18.6% (8/43), while there were no perinatal deaths in the ANA-negative control group. All the perinatal losses were stillbirths. The rate of spontaneous abortions was low in both groups, 2.0 vs. 3.3%, respectively. The ANA titer, complement-fixing activity and antigenic specificity did not correlate with the outcome of the pregnancy. Two infants of the ANA-positive women (3.9%) had a congenital atrioventricular heart block. In both cases the ANA was of the complement fixing type.
© 1994 S. Karger AG, Basel
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Article / Publication Details
Received: January 18, 1993
Accepted: August 09, 1993
Published online: March 01, 2010
Issue release date: 1994
Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0
ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)
For additional information: https://www.karger.com/GOI
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