Gynecologic and Obstetric Investigation

Original Paper

Perinatal Outcome in HIV-Infected Pregnant Women

Semprini A.E.a · Ravizza M.a · Bucceri A.b · Vucetich A.a · Pardi G.a

Author affiliations

aDepartment of Obstetrics and Gynecology, University of Milano Medical School, Ospedale S. Paolo; bUSSL 75/1, Milano, Italy

Related Articles for ""

Gynecol Obstet Invest 1990;30:15–18

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: September 13, 1989
Accepted: December 22, 1989
Published online: March 02, 2010
Issue release date: 1990

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: https://www.karger.com/GOI

Abstract

We have observed 74 HIV-seropositive and 48 HIV-seronegative drug-addicted women and 22 HIV seropositive nondrug-addicted pregnant women during pregnancy and we report their perinatal outcome. 8 out of 96 HIV-seropositive patients had hematological signs of immunodeficiency and 2 of these patients were symptomatic belonging to CDC class III. WE recorded 2 early and 3 late spontaneous abortions, no intrauterine fetal death and 3 neonatal deaths. Seropositive patients had 3 malformed babies, seronegative patients had 1. All these women had a high incidence of premature delivery and intrauterine fetal growth retardation: seropositive patients had a higher incidence of fetuses small for gestational age and a lower incidence of preterm delivery compared to seronegative patients, but the difference was not statistically significant. The incidence of malformation was comparable to the general population: 3 malformed babies were born to HIV-positive drug-addicted mothers, and 1 to a seronegative drug-addicted mother. These findings do not support the hypothesis of a direct detrimental effect of HIV on perinatal outcome. Consequences of fetal exposure to maternal HIV infection involve mostly postnatal life and development of acquired immunodeficiency.

© 1990 S. Karger AG, Basel




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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: September 13, 1989
Accepted: December 22, 1989
Published online: March 02, 2010
Issue release date: 1990

Number of Print Pages: 4
Number of Figures: 0
Number of Tables: 0

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: https://www.karger.com/GOI


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