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Original Paper

Feasibility and Efficiency of Indirect Lifestyle Interventions in Offspring of Type 2 Diabetic Patients

Nishigaki M.a · Ota A.b · Kusakabe T.a · Matsuzaki C.c · Taguchi S.c · Kazuma K.a

Author affiliations

aThe Graduate School of Medicine, School of Health Sciences and Nursing, Department of Adult Nursing/Palliative Care Nursing, The University of Tokyo, Tokyo, bFukuyama Transporting Shibuya Longevity Health Foundation and cBrain Attack Center, Ota Medical Hospital, Fukuyama, Japan

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Public Health Genomics 2011;14:77–84

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: July 22, 2009
Accepted: December 09, 2009
Published online: May 28, 2010
Issue release date: March 2011

Number of Print Pages: 8
Number of Figures: 2
Number of Tables: 2

ISSN: 1662-4246 (Print)
eISSN: 1662-8063 (Online)

For additional information: https://www.karger.com/PHG

Abstract

Introduction: Individuals genetically predisposed to type 2 diabetes represent an important target for preventive strategies. Genetic screening, based on information about individual genetic variants, will be possible technically, but translational research in this field is still insufficient. Family history thus represents a useful tool for detecting genetically high-risk populations in this post-genomic era. Objectives: The purpose of this pilot study was to investigate the feasibility and efficiency of indirect lifestyle interventions in offspring of type 2 diabetic patients. Methods: Offspring were recruited from 74 diabetic (Group 1) and 39 non-diabetic (Group 2, control group) patients. A lifestyle intervention was conducted by mail, a total of 3 times, every 3 months. Lifestyle related to diet and physical activity was assessed using a self-administered questionnaire. Results: Ten offspring of type 2 diabetic and 6 of non-diabetic patients participated in this study. Total energy intake decreased after 3 interventions in both of the groups (Group 1: 305 ± 228.8 kcal/day, p = 0.004; Group 2: 82 ± 65.6 kcal/day, p = 0.04); however, the effect of intervention was significantly greater in Group 1 compared to Group 2 (p = 0.021). Physical activity and other physical outcomes were stable in normal levels during the study period in both of the groups. Conclusions: The intervention program helped to reduce total energy intake in offspring of type 2 diabetic patients more than in the control group, but the acceptance rate of the intervention program was disappointingly low. Further consideration is required to access and motivate offspring to develop precautionary lifestyle principles.

© 2010 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: July 22, 2009
Accepted: December 09, 2009
Published online: May 28, 2010
Issue release date: March 2011

Number of Print Pages: 8
Number of Figures: 2
Number of Tables: 2

ISSN: 1662-4246 (Print)
eISSN: 1662-8063 (Online)

For additional information: https://www.karger.com/PHG


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