Gynecologic and Obstetric Investigation
Original Paper
Lack of Beta-Endorphin Plasma Level Rise in Oxytocin-Induced LaborGenazzani A.R. · Petraglia F. · Facchinetti F. · Galli P.A. · Volpe A.Department of Obstetrics and Gynecology, University of Modena, Italy
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Article / Publication Details
Received: September 18, 1984
Accepted: January 23, 1985
Published online: March 15, 2010
Issue release date: 1985
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)
For additional information: https://www.karger.com/GOI
Abstract
Β-Endorphin (Β-EP), Β-lipotropin (Β-LPH) and cortisol plasma levels were measured during labor in 18 pregnant women. In 7 cases labor progressed spontaneously and in 11 cases oxytocin (5 mlU/min) was administered to stimulate uterine contractions. In control and oxytocin-treated subjects hourly blood samples were taken until delivery. In spontaneous labor all three hormones showed a progressive and significant increase until parturition. In oxytocin-treated patients, however, both Β-EP and Β-LPH remained constant until parturition. Cortisol levels in oxytocin-treated patients presented a significant increase but reached values significantly lower than in control patients. These results indicate that women with uterine hypocontractility during labor requiring oxytocin showed no rise in their plasma Β-EP and Β-LPH and a blunted cortisol rise during oxytocin administration.
© 1985 S. Karger AG, Basel
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Article / Publication Details
Received: September 18, 1984
Accepted: January 23, 1985
Published online: March 15, 2010
Issue release date: 1985
Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0
ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)
For additional information: https://www.karger.com/GOI
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