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Original Paper

The Effects of Antidepressants on the Results of Skin Prick Tests Used in the Diagnosis of Allergic Diseases

Isik S.R.a · Celikel S.a · Karakaya G.a · Ulug B.b · Kalyoncu A.F.a

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aDepartment of Chest Diseases, Adult Allergy Unit and bDepartment of Psychiatry, School of Medicine, Hacettepe University, Ankara, Turkey

Related Articles for ""

Int Arch Allergy Immunol 2011;154:63–68

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: December 22, 2009
Accepted: March 17, 2010
Published online: July 27, 2010
Issue release date: December 2010

Number of Print Pages: 6
Number of Figures: 1
Number of Tables: 3

ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)

For additional information: https://www.karger.com/IAA

Abstract

Background: Some drugs may cause false negative results by suppressing the reactivity of the skin prick tests (SPTs). The aim of this survey was to show whether escitalopram, fluoxetine and sertraline had any effect on the reactivity of SPT. Methods: Twenty-four patients who were admitted to the outpatient clinic of the Psychiatry Department at the Hacettepe University Hospital and planned to be treated by these antidepressants were included in the study between May and October 2008. SPTs with positive control (histamine), negative control and 3 common aeroallergens were performed in the beginning, at the first and fourth weeks. A questionnaire including 26 questions about respiratory symptoms and allergic diseases was filled in face to face by the fellow-in-training. The Visual Analog Scale (VAS) of current respiratory and nasal symptoms was recorded at all 3 visits. Results: There were no statistically significant differences between the 3 mean diameters measured at 3 time points in addition to the mean diameters of the wheals between groups using escitalopram, sertraline and fluoxetine (p > 0.05). There was a statistically significant decrease between the VAS of nasal symptoms at the 3 visits (p < 0.05). Conclusions: Escitalopram, fluoxetine and sertraline do not seem to affect the reactivity of SPTs. Nasal symptoms might have been decreased due to both the allergic treatment suggested and the end of the pollen season.

© 2010 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: December 22, 2009
Accepted: March 17, 2010
Published online: July 27, 2010
Issue release date: December 2010

Number of Print Pages: 6
Number of Figures: 1
Number of Tables: 3

ISSN: 1018-2438 (Print)
eISSN: 1423-0097 (Online)

For additional information: https://www.karger.com/IAA


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