Nephron Clinical Practice
Genetic Variations and Transplant OutcomesKrüger B.a · Schröppel B.baV. Medizinische Klinik, Universitätsklinikum Mannheim, Medizinische Fakultät Mannheim der Universität Heidelberg, Mannheim, Germany; bDivision of Nephrology and Transplantation Institute, Mount Sinai School of Medicine, New York, N.Y., USA
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Nephron Clin Pract 2011;118:c49–c54
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Article / Publication Details
First-Page Preview
Published online: November 11, 2010
Issue release date: November 2010
Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 1
eISSN: 1660-2110 (Online)
For additional information: https://www.karger.com/NEC
Abstract
Extensive genetic variation has been described in molecules regulating innate and adaptive immunity, pharmacokinetics, coagulation, and fibrosis. However, large prospective studies need to be performed to define the clinical consequences of such variation and the potential benefits of genotyping these markers for patients. The purpose of this review is to summarize recent data describing associations of polymorphisms in both immunological and non-immunological molecules with transplant outcomes, and discuss their clinical implications and limitations.
© 2010 S. Karger AG, Basel
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Article / Publication Details
First-Page Preview
Published online: November 11, 2010
Issue release date: November 2010
Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 1
eISSN: 1660-2110 (Online)
For additional information: https://www.karger.com/NEC
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