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Published: October 2010

Open Access Gateway

Repeated Pancreatectomy for Recurrent Pancreatic Carcinoma after Pylorus-Preserving Pancreatoduodenectomy: Report of Two Patients

Ogino T.a · Ueda J.a · Sato N.a · Takahata S.a · Mizumoto K.a · Nakamura M.a · Oda Y.b · Tanaka M.a

Author affiliations

Departments of aSurgery and Oncology and bAnatomic Pathology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

Corresponding Author

Toshitatsu Ogino, MD

Department of Surgery and Oncology, Graduate School of Medical Sciences

Kyushu University, 3-1-1 Higashiku Maedashi, Fukuoka (Japan)

E-Mail ogino924@surg1.med.kyushu-u.ac.jp

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Case Rep Gastroenterol 2010;4:429–434

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Repeated pancreatectomy for pancreatic carcinoma is extremely rare. We report two such patients who underwent pancreatectomy for carcinoma developing in the pancreatic remnant after pylorus-preserving pancreatoduodenectomy (PpPD) for invasive pancreatic ductal carcinoma. One patient underwent PpPD for invasive pancreatic ductal carcinoma and received adjuvant chemotherapy. Follow-up computed tomography (CT) demonstrated a low-density mass in the remnant pancreas, which was diagnosed as a carcinoma by endoscopic ultrasound-guided fine-needle aspiration cytology 5 years 10 months after PpPD. She underwent curative resection of the remnant pancreas and is alive and well 13 months after the second operation. The other patient underwent PpPD for invasive pancreatic ductal carcinoma. Follow-up CT showed a low-density mass in the remnant pancreas after 2 years 11 months. He received systemic chemotherapy with S-1 for 3 months. The tumor shrank, and the patient underwent curative resection of the remnant pancreas 3 years 1 month after the initial operation. Repeated pancreatectomy may provide a chance of long survival for patients with carcinoma developing in the remnant pancreas after pancreatectomy if the recurrence occurring at long term is limited to the remnant pancreas.

© 2010 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Published: October 2010

Published online: October 09, 2010
Issue release date: September – December

Number of Print Pages: 6
Number of Figures: 5
Number of Tables: 0

eISSN: 1662-0631 (Online)

For additional information: http://www.karger.com/CRG

Open Access License / Drug Dosage / Disclaimer

Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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