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Original Paper

Panton-Valentine Leukocidin-Positive Staphylococcus aureus Strains Are Associated with Follicular Skin Infections

Del Giudice P.a · Bes M.b–d · Hubiche T.a · Blanc V.e · Roudière L.a · Lina G.b–d · Vandenesch F.b–d · Etienne J.b–d

Author affiliations

aService d’Infectiologie-Dermatologie, Hôpital Bonnet, Fréjus, bCentre National de Référence des Staphylocoques, Université Lyon 1, and cINSERM U851, IFR128, Lyon, dCentre de Biologie Est, Hospices Civils de Lyon, Bron, and eCentre Hospitalier d’Antibes-Juan-les-Pins, Antibes, France

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Dermatology 2011;222:167–170

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: October 15, 2010
Accepted: December 30, 2010
Published online: February 22, 2011
Issue release date: May 2011

Number of Print Pages: 4
Number of Figures: 1
Number of Tables: 1

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: https://www.karger.com/DRM

Abstract

Background/Aims: Panton-Valentine leukocidin (PVL)-positive Staphylococcus aureus have been associated with suppurative infections; however, their precise role in skin infections has not been elucidated. We studied the rate of PVL-positive S. aureus in the different types of skin infections and compared follicular to nonfollicular skin infections. Methods: In our institution, patients with a skin infection caused by S. aureus were enrolled in a prospective, observational cohort study (from July 1, 2003 to June 30, 2010). We studied the rate of PVL-positive S. aureus in the different clinical types of skin infections and compared the rate of PVL-positive S. aureus in follicular infections to that in nonfollicular infections. Results: A total 229 skin infections were included: 97 (42.5%) were caused by PVL-positive strains. Thirty-nine of the 53 (74%) follicular infections [8 of the 17 (47%) with folliculitis, 30 of the 35 (85.5%) with furuncles and 1 with a carbuncle (100%)] were caused by PVL-positive S. aureus, compared to 16 of the 131 (12%) nonfollicular infections (p < 0.001). Conclusion: PVL-positive S. aureus strains are mainly associated with follicular skin infections.

© 2011 S. Karger AG, Basel


References

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: October 15, 2010
Accepted: December 30, 2010
Published online: February 22, 2011
Issue release date: May 2011

Number of Print Pages: 4
Number of Figures: 1
Number of Tables: 1

ISSN: 1018-8665 (Print)
eISSN: 1421-9832 (Online)

For additional information: https://www.karger.com/DRM


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