Pure Small Cell Carcinoma of the Prostate: A Case Report and Literature ReviewCapizzello A.a · Peponi E.a · Simou N.b · Ntaskagiannis D.a · Tasiou I.a · Kamina S.b · Tsekeris P.a
aRadiation Therapy Department and bPathology Department, University Hospital of Ioannina, Ioannina, Greece
Radiation Therapy Department, University Hospital of Ioannina
L. Staurou Niarxou, GR–45500 Ioannina (Greece)
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Primary small cell carcinoma of the prostate (SCPCa) is a rare pathologic entity with unique clinical features and a poor prognosis. We present a case of a patient diagnosed with pure SCPCa treated with a combined chemo-radiotherapeutic approach. Pathological findings showed that the neoplastic cells exhibited positivity for pancytokeratin, synaptophysin, thyroid transcription factor-1 and CD56. Immunostaining for prostate-specific antigen was negative, while serum prostate-specific antigen was within normal limits. We review the available literature to gain additional information about diagnosis, treatment and prognosis of pure SCPCa.
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