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Review Article · Übersichtsarbeit

Free Access

Organ Preservation: Current Concepts and New Strategies for the Next Decade

Guibert E.E.a · Petrenko A.Y.b · Balaban C.L.a · Somov A.Y.b · Rodriguez J.V.a · Fuller B.J.c

Author affiliations

aCentro Binacional (Argentina-Italia) de Investigaciones en Criobiología Clínica y Aplicada (CAIC), Universidad Nacional de Rosario, Argentina; bDepartment of Cryobiochemistry, Institute for Problems of Cryobiology and Cryomedicine, Ukraine Academy of Sciences, Kharkov, Ukraine; cCell, Tissue and Organ Preservation Unit, Department of Surgery & Liver Transplant Unit, UCL Medical School, Royal Free Hospital Campus, London, UK

Corresponding Author

Prof. Dr. Barry J. Fuller, Cell, Tissue and Organ Preservation Unit, Department of Surgery & Liver Transplant Unit, UCL Medical School, Royal Free Hospital Campus, Pond Street, London NW3 2QG, UK, b.fuller@medsch.ucl.ac.uk

Related Articles for ""

Transfus Med Hemother 2011;38:125–142

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Abstract

Organ transplantation has developed over the past 50 years to reach the sophisticated and integrated clinical service of today through several advances in science. One of the most important of these has been the ability to apply organ preservation protocols to deliver donor organs of high quality, via a network of organ exchange to match the most suitable recipient patient to the best available organ, capable of rapid resumption of life-sustaining function in the recipient patient. This has only been possible by amassing a good understanding of the potential effects of hypoxic injury on donated organs, and how to prevent these by applying organ preservation. This review sets out the history of organ preservation, how applications of hypothermia have become central to the process, and what the current status is for the range of solid organs commonly transplanted. The science of organ preservation is constantly being updated with new knowledge and ideas, and the review also discusses what innovations are coming close to clinical reality to meet the growing demands for high quality organs in transplantation over the next few years.

© 2011 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Review Article · Übersichtsarbeit

Received: January 16, 2011
Accepted: January 26, 2011
Published online: March 21, 2011
Issue release date: April 2011

Number of Print Pages: 18
Number of Figures: 0
Number of Tables: 0

ISSN: 1660-3796 (Print)
eISSN: 1660-3818 (Online)

For additional information: https://www.karger.com/TMH


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