American Journal of Nephrology

Original Report: Patient-Oriented, Translational Research

Clinical Characteristics and Cardiovascular Outcomes of Hemodialysis Patients with Atrial Fibrillation: A Prospective Follow-Up Study

Fujii H.a · Kim J.-I.b · Yoshiya K.c · Nishi S.a · Fukagawa M.a, d

Author affiliations

aDivision of Nephrology and Kidney Center, Kobe University Graduate School of Medicine, bDivision of Nephrology, Chibune Kidney and Dialysis Clinic, Osaka, cDivision of Nephrology, Hara Urology Hospital, Kobe, and dDivision of Nephrology and Metabolism, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan

Keywords: Atrial fibrillationMortalityHemodialysis patients

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Am J Nephrol 2011;34:126–134
https://doi.org/10.1159/000329118

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Article / Publication Details

First-Page Preview
Abstract of Original Report: Patient-Oriented, Translational Research

Received: March 13, 2011
Accepted: May 03, 2011
Published online: June 30, 2011
Issue release date: August 2011

Number of Print Pages: 9
Number of Figures: 2
Number of Tables: 6

ISSN: 0250-8095 (Print)
eISSN: 1421-9670 (Online)

For additional information: https://www.karger.com/AJN

Abstract

Background/Aims: Among the cardiovascular complications in dialysis patients, atrial fibrillation (AF) is the most common arrhythmia. The purpose of this study was to clarify the characteristics and mortality of hemodialysis patients with AF, which are not completely elucidated. Methods: The prevalence of AF in patients undergoing hemodialysis in our institutions was assessed. Patients with AF (AF group) and without AF (control group) were included in this study. Patients in the control group were matched for several important clinical risk factors. For further analysis, AF patients were divided into two groups on the basis of the type of AF (chronic AF (CAF) and paroxysmal AF (PAF) groups). These patients were evaluated for their clinical characteristics, laboratory data and echocardiographic parameters and prospectively followed up for 48 months. Results: Among 328 study patients, 30 had AF (9.1%). Left atrial diameter (LAD) and the left ventricular mass index were significantly greater in the AF group than in the control group. Furthermore, cardiovascular and all-cause mortality and cumulative incidence of cardiovascular events were significantly higher in the AF group than in the control group, and tended to be higher in the CAF group. Conclusions: Our findings demonstrated that the prevalence of AF as 9.1% in hemodialysis patients, and that AF, especially CAF, were associated with high mortality.

© 2011 S. Karger AG, Basel



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Article / Publication Details

First-Page Preview
Abstract of Original Report: Patient-Oriented, Translational Research

Received: March 13, 2011
Accepted: May 03, 2011
Published online: June 30, 2011
Issue release date: August 2011

Number of Print Pages: 9
Number of Figures: 2
Number of Tables: 6

ISSN: 0250-8095 (Print)
eISSN: 1421-9670 (Online)

For additional information: https://www.karger.com/AJN

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2011, Vol.34, No. 2

August 2011

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This study was presented in part at the annual meeting of the European Renal Association-European Dialysis and Transplant Association Congress, 2010.
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