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Short Communication

Free Access

Growing Bacteria Shed Elicitors of Drosophila Humoral Immunity

Karlsson J. · Oldenvi S. · Fahlander C. · Daenthanasanmak A. · Steiner H.

Author affiliations

Department of Genetics, Microbiology and Toxicology, Stockholm University, Stockholm, Sweden

Corresponding Author

Dr. Håkan Steiner

Department of Genetics, Microbiology and Toxicology

Stockholm University

SE–106 91 Stockholm (Sweden)

Tel. +46 8 164 161, E-Mail hakan.steiner@gmt.su.se

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J Innate Immun 2012;4:111–116

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It has been much debated how the Drosophila immune system can recognize bacterial peptidoglycan that is often hidden. We show that bacteria separated from Drosophila S2 cells by a semipermeable membrane can upregulate the Imd pathway. Supernatants from exponentially growing but not from stationary-phase bacterial cultures induce antimicrobial peptides. It is also made likely that the shed elicitors are of peptidoglycan nature.

© 2011 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Short Communication

Received: December 21, 2010
Accepted: May 10, 2011
Published online: August 09, 2011
Issue release date: December 2011

Number of Print Pages: 6
Number of Figures: 3
Number of Tables: 0

ISSN: 1662-811X (Print)
eISSN: 1662-8128 (Online)

For additional information: https://www.karger.com/JIN

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