Quantitative defects of the enamel are considered risk factors for caries development at the cavitated level. Since caries risk assessment and control should be implemented as early as possible in order to prevent operative treatment, it seemed interesting to investigate the relationship between enamel defects and caries development in the stages of progression that precede cavitation. The impact of enamel defects and selected child-mother indicators on early caries development was investigated in a cohort of Brazilian preschool children. The null hypothesis that developmental defects of the enamel and dental caries are independent and that an association between them occurs by chance was tested. The sample (n = 1,718) was made up of 2- to 5-year-olds. Developmental defects of enamel and caries on buccal surfaces were identified in 48 and 26% of the children, respectively. Bivariate analyses at the surface level showed neither an association between demarcated/diffuse opacity and caries experience (p ≧ 0.64, GLM), nor between the presence of hypoplastic surfaces and non-cavitated lesions (p = 0.29, GLM). The multivariate analyses indicated that in the mouths of individual children, hypoplastic surfaces were more likely to present filled surfaces and non-cavitated/cavitated lesions than non-hypoplastic surfaces (within-child p = 0.03, GEE). However, children having teeth with hypoplastic surfaces were not at higher caries risk than those children who did not present hypoplastic surfaces (between-child p = 0.23, GEE). The null hypothesis could not be accepted for quantitative defects such as hypoplasia, since they had a significant impact on the within-child prevalence of filled surfaces and non-cavitated/cavitated lesions.

Keywords:
Developmental defects, Early childhood caries, Non-cavitated lesions, Risk indicators
1.
CASEB (Companhia de Saneamento Ambiental do Distrito Federal): DRSA (report). Brasília, CAESB, 2006.
2.
Carvalho JC, Mestrinho HD, Barreto AC, Maltz M: Onset, development and arrest of dental caries in Brazilian pre-school children. J Clin Oral Invest 1998;2:96–100.
3.
Carvalho JC, Figueiredo MJ, Vieira EO, Mestrinho HD: Caries trends in Brazilian non privileged preschool children in 1996 and 2006. Caries Res 2009a;43:2–9.
4.
Carvalho JC, Figueiredo CS, Mestrinho HD: Clinical report on plaque formation, distribution and maturation within the primary, mixed and permanent dentitions. Eur J Paediatr Dent 2009b;10:193–199.
5.
Chaves AMB, Rosenblatt A, Oliveira OFB: Enamel defects and its relation to life course events in primary dentition of Brazilian children: a longitudinal study. Community Dent Health 2007;24:31–36.
6.
Ekanayake L, van der Hoek W: Prevalence and distribution of enamel defects and dental caries in a region with different concentrations of fluoride in drinking water in Sri Lanka. Int Dent J 2003;53:243–248.
7.
Elfrink MEC, Schuller AA Weerheijm KL, Veerkamp JSJ: hypomineralized second primary molars: prevalence data in Dutch 5-year-olds. Caries Res 2008;42:282–285.
8.
Fédération Dentaire Internationale Working Group: A review of developmental defects of the enamel dental index (DDE Index). Commission on Oral Health, Research & Epidemiology. Int Dent J 1992;42:411–426.
9.
Hoffman RHS, Sousa MLR, Cypriano S: Prevalence of enamel defects and the relationship to dental caries in deciduous and permanent dentition in Indaiatuba, São Paulo, Brazil. Cad Saúde Pública 2007;23:435–444.
10.
Holt RD, Morris CE, Winter GB, Downer MC: Enamel opacities and dental caries in children who used a low fluoride toothpaste between 2 and 5 years of age. Int Dent J 1994;44:331–334.
11.
Hong L, Levy SM, Warren JJ, Broffit B: Association between enamel hypoplasia and dental caries in primary secondary molars: a cohort study. Caries Res 2009;43:345–353.
12.
Kanagaratnam S, Schluter P, Durward C, Mahood R, Mackay T: Enamel defects and dental caries in 9-year-old children living in fluoridated and non fluoridated areas of Auckland, New Zealand. Community Dent Oral Epidemiol 2009;37:250–259.
13.
Koch G, Thesleff I: Developmental disturbances in number and shape of teeth and their treatment; in Koch G, Poulsen S (ed): Pediatric Dentistry – A Clinical Approach. Oxford, Blackwell Munksgaard, 2003, pp 253–271.
14.
Li Y, Navia JM, Caufield PW: Colonization by mutans streptococci in the mouths of 3- and 4-year-old Chinese children with or without enamel hypoplasia. Arch Oral Biol 1994;39:1057–1062.
15.
Li Y, Navia JM, Bian JY: Caries experience in deciduous dentition of rural Chinese children 3–5 years old in relation to the presence or absence of enamel hypoplasia. Caries Res 1996;30:8–15.
16.
Lunardelli SE, Peres MA: Prevalence and distribution of developmental enamel defects in the primary dentition of pre-school children. Braz Oral Res 2005;19:144–149.
17.
Lunardelli SE, Peres MA: Breast-feeding and other mother-child factors associated with developmental enamel defects in the primary teeth of Brazilian children. J Dent Child 2006;73:70–78.
18.
Mancl LA, Leroux BG, DeRouen TA: Between-subject and within-subject statistical information in dental research. J Dent Res 2000;79:1778–1781.
19.
Milgrom P, Riedy CA, Weinstein P, Tanner ACR, Manibusan L, Bruss J: Dental caries and its relationship to bacterial infection, hypoplasia, diet, and oral hygiene in 6- to 36-month-old children. Community Dent Oral Epidemiol 2000;28:295–306.
20.
Milsom KM, Woodward M, Haran D, Lennon MA: Enamel defects in the deciduous dentition as a potential predictor of defects in the permanent dentition of 8- and 9-year-old children in fluoridated Cheshire, England. J Dent Res 1996;75:1015–1018.
21.
Oliveira AFB, Chaves AMB, Rosenblatt A: The influence of enamel defects on the development of early childhood caries in a population with low socioeconomic status: a longitudinal study. Caries Res 2006;40:296–302.
22.
Peres MA, de Oliveira Latorre MC, Sheiham A, Peres KG, Barros FC, Hernandez PG, Maas AM, Romano AR, Victora CG: Social and biological early life influence on severity of dental caries in children aged 6 years. Community Dent Oral Epidemiol 2005;33:53–63.
23.
Seow KW: A study of the development of the permanent dentition in very low birth weight children. J Pediatr Dent 1996;18:379–384.
24.
Seow KW, Clifford H, Battistutta D, Morawska A, Holcombe T: Case-control study on early childhood caries in Australia. Caries Res 2009;43:25–35.
25.
Slayton RL, Warren JJ, Kanellis MJ, Levy SM, Islam M: Prevalence of enamel hypoplasia and isolated opacities in the primary dentition. J Ped Dent 2001;23:32–36.
26.
Weeks KJ, Milsom KM, Lennon MA: Enamel defects in 4 to 5-year-old children in fluoridated and non-fluoridated parts of Cheshire, UK. Caries Res 1993;27:317–320.
27.
Wong HM, McGrath C, Lo ECM, King NM: Association between developmental defects of enamel and different concentrations of fluoride in the public water supply. Caries Res 2006;40:481–486.
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2011
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