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Published: July 2011

Open Access Gateway

Mediastinal Schwannoma Diagnosed by Endoscopic Ultrasonography-Guided Fine Needle Aspiration Cytology

Pakseresht K.a · Reddymasu S.C.a · Oropeza-Vail M.M.a · Fan F.b · Olyaee M.a

Author affiliations

aDepartment of Medicine, Division of Gastroenterology, and bDepartment of Pathology, University of Kansas Medical Center, Kansas City, Kans., USA

Corresponding Author

Savio C. Reddymasu, MD

Department of Medicine, University of Kansas Medical Center

3901 Rainbow Boulevard, Kansas City, KS 66160 (USA)

Tel. +1 913 588 6003, E-Mail sreddymasu@kumc.edu

Related Articles for ""

Case Rep Gastroenterol 2011;5:411–415

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Schwannoma is the most common neurogenic tumor that is derived from the peripheral nerve sheath. There are no specific serologic markers or characteristic imaging abnormalities associated with schwannoma. Tissue diagnosis and immunohistochemistry are required to diagnose this lesion. We describe a 65-year-old male with a finding of three mass lesions in the superior and middle mediastinum on computed tomography of the chest. The largest lesion measured 4.6 × 5 cm. The patient subsequently underwent endoscopic ultrasonography-guided fine needle aspiration (EUS-FNA) of the lesion and cytology was consistent with spindle cell neoplasm. Immunohistochemical staining of the cytologic specimen was positive for S-100 and negative for pan-cytokeratin, CD34, CD117, calcitonin, smooth muscle actin and desmin. These findings were consistent with schwannoma. This is the second reported case of a mediastinal schwannoma diagnosed by EUS-FNA.

© 2011 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Published: July 2011

Published online: July 21, 2011
Issue release date: May – August

Number of Print Pages: 5
Number of Figures: 3
Number of Tables: 0

eISSN: 1662-0631 (Online)

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