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Published: January 2012

Open Access Gateway

Spindle and Giant Cell Type Undifferentiated Carcinoma of the Proximal Bile Duct

Ide T.a · Miyoshi A.a · Kitahara K.a · Kai K.a, b · Noshiro H.a

Author affiliations

Departments of aSurgery and bPathology and Microbiology, Saga University Faculty of Medicine, Saga, Japan

Corresponding Author

Takao Ide

Department of Surgery, Saga University Faculty of Medicine

5-1-1 Nabeshima, Saga 849-8501 (Japan)

Tel. +81 952 342 349, E-Mail idetaka@cc.saga-u.ac.jp

Related Articles for ""

Case Rep Gastroenterol 2012;6:33–39

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Undifferentiated spindle and giant cell carcinoma is an extremely rare malignant neoplasm arising in the extrahepatic bile duct. We herein present the case of a 67-year-old male who developed an undifferentiated spindle and giant cell carcinoma of the proximal bile duct. A nodular infiltrating tumor was located at the proximal bile duct, resulting in obstructive jaundice. Histologically, the tumor was composed of mainly spindle-shaped and giant cells and showed positive immunoreactivity for both cytokeratin and vimentin. Adjuvant chemotherapy was administered following extrahepatic bile duct resection, and he has been doing well for 16 months since the surgical treatment. The literature on this rare malignancy is also reviewed and discussed.

© 2012 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Published: January 2012

Published online: January 16, 2012
Issue release date: January – April

Number of Print Pages: 7
Number of Figures: 3
Number of Tables: 1

eISSN: 1662-0631 (Online)

For additional information: http://www.karger.com/CRG

Open Access License / Drug Dosage / Disclaimer

Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
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