Blood Purification

Original Paper

Heart Rate Variability in Peritoneal Dialysis Patients: What Is the Role of Residual Renal Function?

Tang W.a · Li L.-X.b · Pei J.a · Wang T.a

Author affiliations

aDivision of Nephrology, Peking University Third Hospital, Beijing, and bGuangzhou Nansha District Hospital of Traditional Chinese Medicine, Guangzhou, PR China

Keywords: Autonomic nerve functionHeart rate variabilityPeritoneal dialysisResidual renal function

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Blood Purif 2012;34:58–66
https://doi.org/10.1159/000338184

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: August 15, 2011
Accepted: March 18, 2012
Published online: August 24, 2012
Issue release date: September 2012

Number of Print Pages: 9
Number of Figures: 2
Number of Tables: 4

ISSN: 0253-5068 (Print)
eISSN: 1421-9735 (Online)

For additional information: https://www.karger.com/BPU

Abstract

Background: The relationship between heart rate variability (HRV) and residual renal function (RRF) has not been elucidated previously. Methods: In this cross-sectional study, HRV was evaluated in 71 peritoneal dialysis patients. Patients were divided into RRF decline group, RRF stable group and anuric group. Results: RRF was negatively correlated with SDNN (r = –0.284, p = 0.017), TP (r = –0.247, p = 0.039), and HF (r = –0.238, p = 0.047). Significant sympathetic nerve activation was found in the RRF decline group (significantly lower SDNN, SDSD, RMSSD, pNN50, LF, HF, TP and higher LF/HF ratio) as compared to the RRF stable and anuric groups. Besides, significantly parasympathetic activation was found in the anuric group (the lowest LF/HF ratio as compared to the other groups (both p < 0.05). Multivariate stepwise regression analysis showed that the status of RRF was an independent factor associated with HRV parameters. Conclusion: This study showed autonomic nervous function in peritoneal dialysis patients was associated with a different status of RRF.

© 2012 S. Karger AG, Basel



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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: August 15, 2011
Accepted: March 18, 2012
Published online: August 24, 2012
Issue release date: September 2012

Number of Print Pages: 9
Number of Figures: 2
Number of Tables: 4

ISSN: 0253-5068 (Print)
eISSN: 1421-9735 (Online)

For additional information: https://www.karger.com/BPU

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2012, Vol.34, No. 1

September 2012

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