Original Research Article
The Reliability and Validity of the Mini-Mental State Examination in the Elderly Croatian PopulationBoban M.a,b · Malojčić B.a,b · Mimica N.b,c · Vuković S.b · Zrilić I.b · Hof P.R.e · Šimić G.b,d
aDepartment of Cognitive Neurology, University Hospital Centre, bSchool of Medicine, University of Zagreb, cUniversity Psychiatric Hospital Vrapče, and dCroatian Institute for Brain Research, Zagreb, Croatia; eMount Sinai School of Medicine, New York, N.Y., USA
Marina Boban, MD, PhD
University Department of Cognitive Neurology
Zagreb School of Medicine and University Hospital Centre
Kišpatićeva 12, HR–10000 Zagreb (Croatia)
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Aim: The aim of this study was standardization and validation of the Mini-Mental State Examination (MMSE) in the general Croatian aging population. Methods: Three-hundred and forty-four participants underwent the MMSE test, 217 cognitively healthy subjects without neurological and psychiatric disorders and 127 patients with mild cognitive impairment (MCI) or dementia. Results: The optimal cutoff point for screening of the general Croatian population (cognitively healthy vs. MCI and dementia) is 26/27; in the Croatian population aged ≥65 years, the cutoff point is 24/25, whereas for screening of highly educated persons (≥14 years of education) aged ≥65 years a higher cutoff point should be used (26/27). Conclusions: MMSE results when standardized and validated in a certain population might better contribute to recognition of the individuals at risk that should be directed to dementia outpatient clinics.
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