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Published: September 2012

Open Access Gateway

Surgical Procedure for Sporadic Colorectal Cancer in Patients with Mild Ulcerative Colitis

Uchino M.a · Ikeuchi H.a · Matsuoka H.a · Bando T.a · Hirata A.a · Yasukawa S.c · Takesue Y.b · Tomita N.a

Author affiliations

aDepartment of Lower Gastroenterological Surgery and bDivision of Infection Control and Prevention, Hyogo College of Medicine, Nishinomiya, and cDepartment of Surgical Pathology, Kyoto Prefectural University of Medicine, Kyoto, Japan

Corresponding Author

Motoi Uchino, MD, PhD

Department of Lower Gastroenterological Surgery, Hyogo College of Medicine

Mukogawa-cho, Nishinomiya, Hyogo 663-8501 (Japan)

E-Mail motoi.uchino@nifty.ne.jp

Related Articles for ""

Case Rep Gastroenterol 2012;6:635–642

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Restorative proctocolectomy is recognized as the standard procedure for colitic cancer in patients with ulcerative colitis (UC). However, whether this represents the optimal procedure for UC patients with sporadic cancer remains questionable, as functional quality of life differs substantially between patients with proctocolectomy and partial resection. This study considered possible problems associated with sporadic cancer in UC. Case 1 is a 55-year-old man with a 3-year history of UC who was treated with endoscopic resection for sporadic adenocarcinoma in the rectum. Low anterior resection was subsequently performed due to deep invasion. The final diagnosis was pT3. Differentiating between histopathological diagnoses of sporadic and colitic cancer was difficult. Case 2 is a 71-year-old woman with a 6-year history of UC who was diagnosed with type 1 sporadic sigmoid colon cancer. Dementia and umbilical hernia were present as complications. Total colectomy was performed in consideration of the coexisting complications. Although partial resection for sporadic cancer could be favorable in mild colitis, further immunosuppressive treatments have the potential to elevate the risk of recurrence for advanced cancer. Restorative proctocolectomy may be safer to avoid further recurrent colitis and cancer except in elderly patients or those with other complications.

© 2012 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Published: September 2012

Published online: September 29, 2012
Issue release date: September – December

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 0

eISSN: 1662-0631 (Online)

For additional information: http://www.karger.com/CRG

Open Access License / Drug Dosage / Disclaimer

Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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