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Published: September 2012

Open Access Gateway

Lymphoepithelial Cyst of the Pancreas

Domen H.a · Ohara M.a · Kimura N.b · Takahashi M.a · Yamabuki T.a · Komuro K.a · Iwashiro N.a · Ishizaka M.a

Author affiliations

Departments of aSurgery and bPathology, National Hospital Organization Hakodate Hospital, Hakodate, Japan

Corresponding Author

Hiromitsu Domen, MD

Department of Surgery, National Hospital Organization Hakodate Hospital

18-16, Kawahara-cho, Hakodate 041-8512 (Japan)

E-Mail dynamed2004-websurg@yahoo.co.jp

Related Articles for ""

Case Rep Gastroenterol 2012;6:604–611

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Cystic lesions of the pancreas can be divided into true cysts, pseudocysts, and cystic neoplasms. Lymphoepithelial cysts (LECs) are a type of true cyst that can mimic pseudocysts and cystic neoplasms. LECs are rare lesions; fewer than 90 cases have been reported in the English language literature. The case of a 60-year-old man with an LEC of the pancreas is reported. He was admitted with upper abdominal discomfort. Computed tomography showed a 64 × 39 mm cystic mass in the retroperitoneum behind the duodenum and inferior caval vein. Magnetic resonance imaging revealed a right-sided mass on T1-weighted imaging, with a clear boundary between the mass and its surroundings, except for the pancreas. The mass had an inhomogeneous intensity on T2-weighted imaging. Within the mass, small floating nodules with low intensity were seen. Endoscopic ultrasound showed many high-echoic nodules and smaller grains scattered everywhere in the mass. Fine needle aspiration and cytologic examination were performed. Characteristic chylaceous fluid was obtained in which anucleate squamous cells were found. There were also a few atypical large cells with irregularly shaped marked nucleoli and degenerative cytoplasm. Cytologic diagnosis was suspicious for malignancy. The lesion was diagnosed as a retroperitoneal cyst, probably of pancreatic origin. Since a neoplastic lesion could not be ruled out, surgery was performed. The lesion was palpable on the dorsal side of the second portion of the duodenum. The mass was completely resected. Macroscopically, the lesion was a multilocular cyst with a thin septal wall. The cyst was filled with cottage cheese-like substance. Microscopically, the cyst wall was composed of stratified squamous epithelium and dense subepithelial lymphatic tissue with developed lymph follicles. The epithelial cells had no atypia. The histopathologic diagnosis was LEC of the pancreas. The patient’s postoperative course was good.

© 2012 S. Karger AG, Basel

Article / Publication Details

First-Page Preview
Abstract of Published: September 2012

Published online: September 24, 2012
Issue release date: September – December

Number of Print Pages: 8
Number of Figures: 3
Number of Tables: 0

eISSN: 1662-0631 (Online)

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Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
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