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Clinical Study

Preoperative Magnetoencephalographic Sensory Cortex Mapping

Niranjan A. · Laing E.J.C. · Laghari F.J. · Richardson R.M. · Lunsford L.D.

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Department of Neurological Surgery, University of Pittsburgh and UPMC Brain Mapping Center, Pittsburgh, Pa., USA

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Stereotact Funct Neurosurg 2013;91:314-322

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Article / Publication Details

First-Page Preview
Abstract of Clinical Study

Received: May 24, 2012
Accepted: January 20, 2013
Published online: June 22, 2013
Issue release date: September 2013

Number of Print Pages: 9
Number of Figures: 4
Number of Tables: 1

ISSN: 1011-6125 (Print)
eISSN: 1423-0372 (Online)

For additional information: https://www.karger.com/SFN

Abstract

The use of functional neuroimaging holds the promise of improving neurosurgical outcomes by providing preoperative localization of critical brain functions. The brain representation of somatosensory function can be effectively localized using magnetoencephalography (MEG) in both normal subjects and in patients with tumors, vascular malformation, and epilepsy. This study investigates the pattern of somatosensory localization in 45 patients. Thirty-two of these patients underwent subsequent resective surgery for brain pathologies. Electrical stimulation of the median nerve was conducted, and the most prominent somatosensory peak in the resultant averaged data was localized using the single equivalent current dipole technique. Results showed that this peak localized either to the central or postcentral sulcus of the somatosensory cortex. We found that neither age nor the presence of brain pathologies had significant effect on the recognition of the somatosensory cortex. Patients who underwent surgery after presurgical planning using MEG suffered no new somatosensory deficits, indicating the valuable role of pre-surgical mapping using MEG in the surgical planning.

© 2013 S. Karger AG, Basel


References

  1. Gallen CC, Hirschkoff EC, Buchanan DS: Magnetoencephalography and magnetic source imaging. Capabilities and limitations. Neuroimaging Clin N Am 1995;5:227-249.
    External Resources
  2. Ganslandt O, Ulbricht D, Kober H, Vieth J, Strauss C, Fahlbusch R: SEF-MEG localization of somatosensory cortex as a method for presurgical assessment of functional brain area. Electroencephalogr Clin Neurophysiol Suppl 1996;46:209-213.
    External Resources
  3. Kamada K, Takeuchi F, Kuriki S, Oshiro O, Houkin K, Abe H: Functional neurosurgical simulation with brain surface magnetic resonance images and magnetoencephalography. Neurosurgery 1993;33:269-272.
    External Resources
  4. Morioka T, Mizushima A, Yamamoto T, Tobimatsu S, Matsumoto S, Hasuo K, et al: Functional mapping of the sensorimotor cortex: combined use of magnetoencephalography, functional MRI, and motor evoked potentials. Neuroradiology 1995;37:526-530.
  5. Orrison WW, Davis LE, Sullivan GW, Mettler FA Jr, Flynn ER: Anatomic localization of cerebral cortical function by magnetoencephalography combined with MR imaging and CT. Am J Neuroradiol 1990;11:713-716.
    External Resources
  6. Castillo EM, Simos PG, Wheless JW, Baumgartner JE, Breier JI, Billingsley RL, et al: Integrating sensory and motor mapping in a comprehensive MEG protocol: clinical validity and replicability. NeuroImage 2004;21:973-983.
  7. Ganslandt O, Fahlbusch R, Nimsky C, Kober H, Moller M, Steinmeier R, et al: Functional neuronavigation with magnetoencephalography: outcome in 50 patients with lesions around the motor cortex. J Neurosurg 1999;91:73-79.
    External Resources
  8. Morioka T, Yamamoto T, Mizushima A, Tombimatsu S, Shigeto H, Hasuo K, et al: Comparison of magnetoencephalography, functional MRI, and motor evoked potentials in the localization of the sensory-motor cortex. Neurol Res 1995;17:361-367.
    External Resources
  9. Rezai AR, Mogilner AY, Cappell J, Hund M, Llinas RR, Kelly PJ: Integration of functional brain mapping in image-guided neurosurgery. Acta Neurochir Suppl 1997;68:85-89.
  10. Hamalainen MS: Magnetoencephalography: a tool for functional brain imaging. Brain Topography 1992;5:95-102.
  11. Hari R: On brain's magnetic responses to sensory stimuli. J Clin Neurophysiol 1991;8:157-169.
    External Resources
  12. Wienbruch C, Moratti S, Elbert T, Vogel U, Fehr T, Kissler J, et al: Source distribution of neuromagnetic slow wave activity in schizophrenic and depressive patients. Clin Neurophysiol 2003;114:2052-2060.
  13. Disbrow EA, Hinkley LB, Roberts TP: Ipsilateral representation of oral structures in human anterior parietal somatosensory cortex and integration of inputs across the midline. J Comp Neurol 2003;467:487-495.
  14. Karhu J, Hari R, Lu ST, Paetau R, Rif J: Cerebral magnetic fields to lingual stimulation. Electroencephalogr Clin Neurophysiol 1991;80:459-468.
  15. Nihashi T, Kakigi R, Kawakami O, Hoshiyama M, Itomi K, Nakanishi H, et al: Representation of the ear in human primary somatosensory cortex. NeuroImage 2001;13:295-304.
  16. Hari R: Magnetic evoked fields of the human brain: basic principles and applications. Electroencephalogr Clin Neurophysiol Suppl 1990;41:3-12.
    External Resources
  17. Pollok B, Moll M, Schmitz F, Muller K, Schnitzler A: Rapid mapping of finger representations in human primary somatosensory cortex applying neuromagnetic steady-state responses. Neuroreport 2002;13:235-238.
  18. Nakamura A, Yamada T, Goto A, Kato T, Ito K, Abe Y, et al: Somatosensory homunculus as drawn by MEG. NeuroImage 1998;7:377-386.
  19. Kakigi R: Somatosensory evoked magnetic fields following median nerve stimulation. Neurosci Res 1994;20:165-174.
  20. Kakigi R, Koyama S, Hoshiyama M, Shimojo M, Kitamura Y, Watanabe S: Topography of somatosensory evoked magnetic fields following posterior tibial nerve stimulation. Electroencephalogr Clin Neurophysiol 1995;95:127-134.
  21. Itomi K, Kakigi R, Maeda K, Hoshiyama M: Dermatome versus homunculus; detailed topography of the primary somatosensory cortex following trunk stimulation. Clin Neurophysiol 2000;111:405-412.
  22. Liguori R, Taher G, Trojaborg W: Somatosensory evoked potentials from cervical and lumbosacral dermatomes. Acta Neurol Scand 1991;84:161-166.
  23. Kakigi R, Hoshiyama M, Shimojo M, Naka D, Yamasaki H, Watanabe S, et al: The somatosensory evoked magnetic fields. Prog Neurobiol 2000;61:495-523.
  24. Burgess RC, Funke ME, Bowyer SM, Lewine JD, Kirsch HE, Bagic AI: American Clinical Magnetoencephalography Society Clinical Practice Guideline 2: presurgical functional brain mapping using magnetic evoked fields. J Clin Neurophysiol 2011;28:355-361.
    External Resources
  25. Adler G, Nacimiento AC: Age-dependent changes of short-latency somatosensory evoked potentials in healthy adults. Appl Neurophysiol 1988;51:55-59.
  26. Akyuz G, Guven Z, Kayhan O, Ozaras N, Erden E: The effects of age, height and gender on the somatosensory evoked potentials in man. Electromyogr Clin Neurophysiol 1996;36:311-315.
    External Resources
  27. Chu NS: Somatosensory evoked potentials: correlations with height. Electroencephalogr Clin Neurophysiol 1986;65:169-176.
  28. Tanosaki M, Ozaki I, Shimamura H, Baba M, Matsunaga M: Effects of aging on central conduction in somatosensory evoked potentials: evaluation of onset versus peak methods. Clin Neurophysiol 1999;110:2094-2103.
  29. Huttunen J, Wikstrom H, Salonen O, Ilmoniemi RJ: Human somatosensory cortical activation strengths: comparison between males and females and age-related changes. Brain Res 1999;818:196-203.
  30. Stephen JM, Ranken D, Best E, Adair J, Knoefel J, Kovacevic S, et al: Aging changes and gender differences in response to median nerve stimulation measured with MEG. Clin Neurophysiol 2006;117:131-143.
  31. Ganslandt O, Steinmeier R, Kober H, Vieth J, Kassubek J, Romstock J, et al: Magnetic source imaging combined with image-guided frameless stereotaxy: a new method in surgery around the motor strip. Neurosurgery 1997;41:621-627; discussion 7-8.
  32. Rezai AR, Hund M, Kronberg E, Zonenshayn M, Cappell J, Ribary U, et al: The interactive use of magnetoencephalography in stereotactic image-guided neurosurgery. Neurosurgery 1996;39:92-102.

Article / Publication Details

First-Page Preview
Abstract of Clinical Study

Received: May 24, 2012
Accepted: January 20, 2013
Published online: June 22, 2013
Issue release date: September 2013

Number of Print Pages: 9
Number of Figures: 4
Number of Tables: 1

ISSN: 1011-6125 (Print)
eISSN: 1423-0372 (Online)

For additional information: https://www.karger.com/SFN


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