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Review

Role of Next-Generation Sequencing in Understanding the Interactions between Human Papillomavirus and the Cervicovaginal Microbiome

Cervantes J.L.a · Hong B.-Y.b

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Departments of aPediatrics and bPeriodontology, University of Connecticut Health Center, Farmington, Conn., USA

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Gynecol Obstet Invest 2013;76:195-202

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Article / Publication Details

First-Page Preview
Abstract of Review

Received: January 30, 2013
Accepted: April 13, 2013
Published online: May 22, 2013
Issue release date: November 2013

Number of Print Pages: 8
Number of Figures: 1
Number of Tables: 0

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: https://www.karger.com/GOI

Abstract

The applications of next-generation sequencing in the field of human papillomavirus and associated neoplasias have extended beyond the accurate genotyping of human papillomavirus types. Next-generation sequencing is able to provide important information on the interactions of the cervicovaginal microbiome and environment with the virus, and the role that these factors play on its transmission and persistence. The advances in sequencing technologies have greatly contributed to the current knowledge of human cervicovaginal microbiome in recent years, allowing the assessment of microbiome variability between species, individuals and populations.

© 2013 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Review

Received: January 30, 2013
Accepted: April 13, 2013
Published online: May 22, 2013
Issue release date: November 2013

Number of Print Pages: 8
Number of Figures: 1
Number of Tables: 0

ISSN: 0378-7346 (Print)
eISSN: 1423-002X (Online)

For additional information: https://www.karger.com/GOI


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