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Original Paper

A Polysomnographic and Clinical Study of Sleep Disorders in Patients with Behçet and Neuro-Behçet Syndrome

Uygunoğlu U. · Benbir G. · Saip S. · Kaynak H. · Siva A.

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Department of Neurology, Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey

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Eur Neurol 2014;71:115-119

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: January 15, 2013
Accepted: August 25, 2013
Published online: January 21, 2014
Issue release date: April 2014

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 1

ISSN: 0014-3022 (Print)
eISSN: 1421-9913 (Online)

For additional information: https://www.karger.com/ENE

Abstract

Brainstem is the most common site of involvement in neuro-Behçet syndrome (NBS). On the other hand, the critical importance of this anatomical region in the regulation of sleep has been disregarded in the literature. We aimed to investigate the microstructure of sleep in patients with Behçet syndrome (BS) and NBS. Patients were allocated to 2 groups: (1) BS without any neurological involvement and (2) NBS with brainstem lesions only. A control group was also enrolled in this study. The comparison of polysomnographic parameters between all patients (BS and NBS) with the control group showed that sleep onset was longer (p = 0.006), the duration of superficial NREM sleep stage (N2) was significantly longer (p = 0.018), and the respiratory disturbance index was significantly higher (p = 0.034) in patients. Sleep apnea and restless legs syndrome are more commonly observed in BS and NBS. Our findings emphasize the importance of questioning the quality of sleep and its disorders in patients with BS in order to better handle the common somatic complaints in these patients, such as fatigue or daytime sleepiness.

© 2014 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: January 15, 2013
Accepted: August 25, 2013
Published online: January 21, 2014
Issue release date: April 2014

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 1

ISSN: 0014-3022 (Print)
eISSN: 1421-9913 (Online)

For additional information: https://www.karger.com/ENE


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