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The Craniocervical Syndrome and MRI

Editor(s): Smith F.W. (London) 
Dworkin J.S. (Melville, N.Y.) 
Cover

Cerebrospinal Fluid Physiology and Its Role in Neurologic Disease

Bradley W.G.

Author affiliations

Department of Radiology, University of California, San Diego, Calif., USA

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Smith FW, Dworkin JS (eds): The Craniocervical Syndrome and MRI. Basel, Karger, 2015, pp 33-47

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Article / Publication Details

First-Page Preview
Abstract of  

Published online: March 27, 2015
Cover Date: 2015

Number of Print Pages: 15
Number of Figures: 22
Number of Tables: 1

ISBN: 978-3-318-02696-2 (Print)
eISBN: 978-3-318-02697-9 (Online)

Abstract

Idiopathic normal pressure hydrocephalus appears to be a ‘two hit' disease starting out as benign external hydrocephalus in infancy followed by deep white matter ischemia in late adulthood. The arachnoid granulations in infants with benign external hydrocephalus may never mature, leading to a parallel pathway for cerebrospinal fluid resorption through the extracellular space of the brain. This works well until deep white matter ischemia develops in which the myelin protein attracts the polar water molecules, leading to increased resistance to outflow of cerebrospinal fluid and hydrocephalus.

© 2015 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of  

Published online: March 27, 2015
Cover Date: 2015

Number of Print Pages: 15
Number of Figures: 22
Number of Tables: 1

ISBN: 978-3-318-02696-2 (Print)
eISBN: 978-3-318-02697-9 (Online)


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Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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