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Original Research Article

Open Access Gateway

Are There Any Connections between Language Deficits and Cognitive Slowing in Alzheimer's Disease

Schecker M.c · Kochler C.c · Schmidtke K.b · Rauh R.a

Author affiliations

aKlinik für Psychiatrie, Psychotherapie und Psychosomatik im Kindes- und Jugendalter, Universität Freiburg, Freiburg, bKlinik für Hirnleistungsstörungen Klausenbach, Nordrach, and cNeurolinguistisches Labor NLL, Klinik für Psychiatrie, Psychotherapie und Psychosomatik im Kindes- und Jugendalter, Universität Freiburg, Freiburg, Germany

Corresponding Author

Prof. Dr. Michael Schecker

Neurolinguistisches Labor NLL, Klinik für Psychiatrie, Psychotherapie und

Psychosomatik im Kindes- und Jugendalter, Universität Freiburg

Hauptstrasse 1, DE-79104 Freiburg (Germany)

E-Mail michael.schecker@zfn-brain.uni-freiburg.de

Related Articles for ""

Dement Geriatr Cogn Disord Extra 2014;4:442-449

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Abstract

Background: Speech disorders already occur in the early phases of Alzheimer's disease (AD). As a possible cause, problems of executive processes are discussed. Cognitive slowing is also repeatedly addressed. Aims: Are there any connections between cognitive slowing and speech disorders in AD? And is there a relationship between cognitive slowing and executive processes? Methods: The data of 72 healthy controls and 52 AD patients were examined with regard to their language performance and their response times in a computerized Stroop paradigm. Results: The AD patients showed significantly worse results in all language tests as well as much longer reaction times in all Stroop conditions, especially in the interference condition (Stroop 3). Speech errors and response times correlated with severity (MMSE), and the speech errors correlated with the reaction times in Stroop 3 (interference condition, which reflects the processing time of executive processes). Conclusion: The most interesting question now is: How are language processing and executive processing time (Stroop 3) related?

© 2014 S. Karger AG, Basel


Article / Publication Details

First-Page Preview
Abstract of Original Research Article

Published online: November 12, 2014
Issue release date: September – December

Number of Print Pages: 8
Number of Figures: 4
Number of Tables: 5


eISSN: 1664-5464 (Online)

For additional information: http://www.karger.com/DEE


Open Access License / Drug Dosage / Disclaimer

Open Access License: This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
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