Recurrent Breast Relapses in a Patient with Acute Lymphoblastic Leukaemia following Allogeneic Bone Marrow TransplantationSavaşan S.a · Abella E.a,b · Karanes C.b · Ravindranath Y.a
aBarbara Ann Karmanos Cancer Institute, Children’s Hospital of Michigan, Division of Hematology/Oncology, and b Harper Hospital, Division of Hematology/Oncology, Bone Marrow Transplantation Unit, Wayne State University, Detroit, Mich., USA
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Isolated extramedullary relapse is very rare after allogeneic bone marrow transplantation (BMT) in acute lymphoblastic leukaemia (ALL) and continues to be a therapeutic problem. We report recurrent breast relapses in a patient with ALL after allogeneic BMT. On both occasions, bone marrow cells were shown to be of donor origin and masses disappeared after systemic chemotherapy. Treatment of the isolated extramedullary relapse after allogeneic BMT is discussed.
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