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Original Paper

Are All Oscillators Created Equal? In vitro Performance Characteristics of Eight High-Frequency Oscillatory Ventilators

Tingay D.G.a,b,d,e · John J.b · Harcourt E.R.a, c · Black D.a · Dargaville P.A.a, g · Mills J.F.a, b · Davis P.G.a,d,f

Author affiliations

aNeonatal Research, Murdoch Childrens Research Institute, bNeonatology, and cClinical Technology Service, Royal Children's Hospital, and dNeonatal Research, Royal Women's Hospital, Parkville, Vic., eDepartment of Paediatrics, and fDepartment of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Vic., and gDepartment of Paediatrics, Royal Hobart Hospital and University of Tasmania, Hobart, Tas., Australia

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Neonatology 2015;108:220-228

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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: November 11, 2014
Accepted: May 07, 2015
Published online: August 19, 2015
Issue release date: September 2015

Number of Print Pages: 9
Number of Figures: 5
Number of Tables: 1

ISSN: 1661-7800 (Print)
eISSN: 1661-7819 (Online)

For additional information: https://www.karger.com/NEO

Abstract

Background: The mode of waveform generation and circuit characteristics differ between high-frequency oscillators. It is unknown if this influences performance. Objectives: To describe the relationships between set and delivered pressure amplitude (ΔP), and the interaction with frequency and endotracheal tube (ETT) diameter, in eight high-frequency oscillators. Methods: Oscillators were evaluated using a 70-ml test lung at 1.0 and 2.0 ml/cm H2O compliance, with mean airway pressures (PAW) of 10 and 20 cm H2O, frequencies of 5, 10 and 15 Hz, and an ETT diameter of 2.5 and 3.5 mm. At each permutation of PAW, frequency and ETT, the set ΔP was sequentially increased from 15 to 50 cm H2O, or from 20 to 100% maximum amplitude (10% increments) depending on the oscillator design. The ΔP at the ventilator (ΔPVENT), airway opening (ΔPAO) and within the test lung (ΔPTRACH), and tidal volume (VT) at the airway opening were determined at each set ΔP. Results: In two oscillators the relationships between set and delivered ΔP were non-linear, with a plateau in ΔP thresholds noted at all frequencies (Dräger Babylog 8000) or ≥10 Hz (Dräger VN500). In all other devices there was a linear relationship between ΔPVENT, ΔPAO and ΔPTRACH (all r2 >0.93), with differing attenuation of the pressure wave. Delivered VT at the different settings tested varied between devices, with some unable to deliver VT >3 ml at 15 Hz, and others generating VT >20 ml at 5 Hz and a 1:1 inspiratory-to-expiratory time ratio. Conclusions: Clinicians should be aware that modern high-frequency oscillators exhibit important differences in the delivered ΔP and VT.

© 2015 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: November 11, 2014
Accepted: May 07, 2015
Published online: August 19, 2015
Issue release date: September 2015

Number of Print Pages: 9
Number of Figures: 5
Number of Tables: 1

ISSN: 1661-7800 (Print)
eISSN: 1661-7819 (Online)

For additional information: https://www.karger.com/NEO


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