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Editorial

Free Access

Second-Line Chemotherapy in Recurrent Glioblastoma - Still Controversial

Franceschi E.

Author affiliations

Department of Medical Oncology, Bellaria-Maggiore Hospital, Azienda USL of Bologna - IRCCS Institute of Neurological Sciences, Bologna, Italy

Corresponding Author

Dr. Enrico Franceschi

Department of Medical Oncology, Bellaria-Maggiore Hospital

Azienda USL of Bologna - IRCCS Institute of Neurological Sciences

Via Altura 3, 40139 Bologna, Italy

enricofra@yahoo.it

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Oncol Res Treat 2015;38:345-346

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Abstract of Editorial

References

  1. Carvalho BF, Fernandes AC, Almeida DS, et al.: Second-line chemotherapy in recurrent glioblastoma: a 2-cohort study. Oncol Res Treat 2015;38: DOI 10.1159/000431236.
  2. Stark-Vance V: Bevacizumab and CPT-11 in the treatment of relapsed malignant glioma, World Federation of Neuro-Oncology Second Quadrennial Meeting. Edinburgh, Scotland, 2005, abstr 342.
  3. Vredenburgh JJ, Desjardins A, Herndon JE, 2nd, et al.: Bevacizumab plus irinotecan in recurrent glioblastoma multiforme. J Clin Oncol 2007;25:4722-4729.
  4. Kreisl TN, Kim L, Moore K, et al.: Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma. J Clin Oncol 2008;27:740-745.
  5. Friedman HS, Prados MD, Wen PY, et al.: Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J Clin Oncol 2009;27:4733-4740.
  6. Brandes A, Finocchiaro G, Zagonel V, et al.: Randomized phase II trial AVAREG (ML25739) with bevacizumab (BEV) or fotemustine (FTM) in recurrent GBM: final result from the randomized phase II trial. Annals of Oncology 2014;25:iv137.
  7. Taal W, Oosterkamp HM, Walenkamp AM, et al.: Single-agent bevacizumab or lomustine versus a combination of bevacizumab plus lomustine in patients with recurrent glioblastoma (BELOB trial): a randomised controlled phase 2 trial. Lancet Oncol 2014;15:943-953.
  8. Wen PY, Macdonald DR, Reardon DA, et al.: Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group. J Clin Oncol 2010;28:1963-1972.

Article / Publication Details

Received: May 19, 2015
Accepted: May 21, 2015
Published online: July 01, 2015
Issue release date: August 2015

Number of Print Pages: 2
Number of Figures: 0
Number of Tables: 0

ISSN: 2296-5270 (Print)
eISSN: 2296-5262 (Online)

For additional information: https://www.karger.com/ORT


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