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The Essence of Aging

Vijg J.a · Kennedy B.K.b

Author affiliations

aDepartment of Genetics, Albert Einstein College of Medicine, New York, N.Y., and bBuck Institute for Research on Aging, Novato, Calif., USA

Corresponding Author

Jan Vijg, PhD, Professor and Chair

Department of Genetics, Albert Einstein College of Medicine

1301 Morris Park Ave

Bronx, NY 10461 (USA)

E-Mail jan.vijg@einstein.yu.edu

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Gerontology 2016;62:381-385

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The idea that aging is a purposeful, programmed series of events is intuitively appealing based on its many conserved aspects and the demonstrated feasibility of modifying life span by manipulating single genes or pathways. Yet, the case for a nonadaptive basis of aging is strong and now all but generally accepted in the field. Here, we briefly review why the case for programmed aging is weak, with a focus on the lack of possible evolutionary beneficial effects.

© 2015 S. Karger AG, Basel


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Article / Publication Details

First-Page Preview
Abstract of Viewpoint

Received: March 30, 2015
Accepted: August 12, 2015
Published online: September 22, 2015
Issue release date: June 2016

Number of Print Pages: 5
Number of Figures: 0
Number of Tables: 0

ISSN: 0304-324X (Print)
eISSN: 1423-0003 (Online)

For additional information: https://www.karger.com/GER

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