Oncology

Clinical Study

Balloon-Occluded Transcatheter Arterial Chemoembolization for Hepatocellular Carcinoma: A Single-Center Experience

Minami Y.a · Minami T.a · Chishina H.a · Arizumi T.a · Takita M.a · Kitai S.a · Yada N.a · Hagiwara S.a · Tsurusaki M.b · Yagyu Y.b · Ueshima K.a · Nishida N.a · Murakami T.b · Kudo M.a

Author affiliations

Departments of aGastroenterology and Hepatology and bRadiology, Faculty of Medicine, Kinki University, Osaka-Sayama, Japan

Keywords: Balloon-occluded transcatheter arterial chemoembolizationHepatocellular carcinoma

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Oncology 2015;89(suppl 2):27-32
https://doi.org/10.1159/000440628

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Article / Publication Details

First-Page Preview
Abstract of Clinical Study

Published online: November 19, 2015
Issue release date: November 2015

Number of Print Pages: 6
Number of Figures: 1
Number of Tables: 2

ISSN: 0030-2414 (Print)
eISSN: 1423-0232 (Online)

For additional information: https://www.karger.com/OCL

Abstract

Objective: To investigate whether balloon-occluded transcatheter arterial chemoembolization (b-TACE) can produce a more dense accumulation of iodized oil in various stages of hepatocellular carcinoma (HCC), from single to uncountable, to overcome inferior local control. Materials and Methods: We studied 27 patients with HCC, including single to uncountable multiple lesions, who underwent b-TACE between August 2013 and April 2015. Dynamic CT was performed at baseline and 1-3 months after b-TACE. The treatment effect (TE) after b-TACE was evaluated using the Response Evaluation Criteria in Cancer of the Liver (RECICL) proposed by the Liver Cancer Study Group of Japan. Results: In the countable HCC group, contrast-enhanced CT demonstrated RECICL TE4 in 43.8% (14/32), TE3 in 12.5% (4/32), TE2 in 37.5% (12/32), and TE1 in 6.3% (2/32) of patients. For the TACE-naïve cohort, the objective response rate was 52.9%. The objective response rate was 60% for the previously TACE-treated cohort. In the uncountable multiple HCC group, the objective response rate was 0% (0/10), with progressive disease in 90% (9/10) of patients. Conclusion: Our observations suggested that b-TACE did not reduce the efficacy of retreatment for HCC with an insufficient outcome from conventional TACE, but it could not improve the efficacy of treatment for uncountable multiple HCCs.

© 2015 S. Karger AG, Basel



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Article / Publication Details

First-Page Preview
Abstract of Clinical Study

Published online: November 19, 2015
Issue release date: November 2015

Number of Print Pages: 6
Number of Figures: 1
Number of Tables: 2

ISSN: 0030-2414 (Print)
eISSN: 1423-0232 (Online)

For additional information: https://www.karger.com/OCL

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2015, Vol.89, Suppl. 2

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