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Clinical Practice: Original Paper

The Association between Depression, Perceived Health Status, and Quality of Life among Individuals with Chronic Kidney Disease: An Analysis of the National Health and Nutrition Examination Survey 2011-2012

Nguyen H.A.a · Anderson C.A.M.b · Miracle C.M.c · Rifkin D.E.c

Author affiliations

aDepartment of Nephrology and Hypertension, UCSD Medical Center, San Diego, CA, bUCSD Department of Family Medicine and Public Health, La Jolla, CA, and cDepartment of Nephrology and Hypertension, VA San Diego Healthcare System, San Diego, CA, USA

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Nephron 2017;136:127-135

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Article / Publication Details

First-Page Preview
Abstract of Clinical Practice: Original Paper

Received: August 23, 2016
Accepted: January 04, 2017
Published online: March 02, 2017
Issue release date: June 2017

Number of Print Pages: 9
Number of Figures: 2
Number of Tables: 3

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: https://www.karger.com/NEF

Abstract

Background: Depression is the most common mental health disorder among those with end-stage renal disease (ESRD), with prevalence of 15-40%. However, the association between chronic kidney disease (CKD) and depression is more variable. We examined the associations of CKD with depression, perceived health status, and quality of life in the National Health and Nutrition Examination Survey (NHANES) 2011-2012. Methods: This study included 4,075 adults. Depression was defined as a condition when a Patient Health Questionnaire score was ≥10, or when there was reported antidepressant use. Reduced quality of life was defined by the number of days having poor mental and physical health, or feeling anxious. We calculated ORs for associations between CKD and depression and self-perceived health status, and used linear regression to examine associations between CKD and the number of days of poor health or anxiety. Results: The prevalence of CKD was 7.0% and that of depression was 19.1%. Those with CKD were not more likely to be depressed versus those without CKD after multivariate adjustment. Although they were 2.2 times more likely to have fair/poor health status after adjusting for demographic characteristics, this was attenuated by adjustment for confounders. Those with CKD reported one more day of being inactive due to poor health in the past month (p < 0.05), after multivariate adjustment. No differences were found for self-reported anxiety. Conclusion: Our findings suggest that NHANES participants with CKD have more days of poor health but are not more likely to be depressed or anxious. This may reflect differences between clinical CKD populations and community-based samples.

© 2017 S. Karger AG, Basel


References

  1. Hedayati SS, Bosworth HB, Kuchibhatla M, Kimmel PL, Szczech LA: The predictive value of self-report scales compared with physician diagnosis of depression in hemodialysis patients. Kidney Int 2006;69:1662-1668.
  2. Lopes AA, Albert JM, Young EW, Satayathum S, Pisoni RL, Andreucci VE, Mapes DL, Mason NA, Fukuhara S, Wikström B, Saito A, Port FK: Screening for depression in hemodialysis patients: associations with diagnosis, treatment, and outcomes in the DOPPS. Kidney Int 2004;66:2047-2053.
  3. Lacson E Jr, Bruce L, Li NC, Mooney A, Maddux FW: Depressive affect and hospitalization risk in incident hemodialysis patients. Clin J Am Soc Nephrol 2014;9:1713-1719.
  4. Olagunju AT, Campbell EA, Adeyemi JD: Interplay of anxiety and depression with quality of life in endstage renal disease. Psychosomatics 2015;56:67-77.
  5. Blake C, Codd MB, Cassidy A, O'Meara YM: Physical function, employment and quality of life in end-stage renal disease. J Nephrol 2000;13:142-149.
  6. National Kidney Foundation: KDOQI clinical practice guideline for diabetes and CKD: 2012 update. Am J Kidney Dis 2012;60:850-886.
  7. Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS: Prevalence of chronic kidney disease and decreased kidney function in the adult US population: third national health and nutrition examination survey. Am J Kidney Dis 2003;41:1-12.
  8. Coresh J, Selvin E, Stevens LA, Manzi J, Kusek JW, Eggers P, Van Lente F, Levey AS: Prevalence of chronic kidney disease in the United States. JAMA 2007;298:2038-2047.
  9. Balogun RA, Abdel-Rahman EM, Balogun SA, Lott EH, Lu JL, Malakauskas SM, Ma JZ, Kalantar-Zadeh K, Kovesdy CP: Association of depression and antidepressant use with mortality in a large cohort of patients with nondialysis-dependent CKD. Clin J Am Soc Nephrol 2012;7:1793-1800.
  10. Condé SA, Fernandes N, Santos FR, Chouab A, Mota MM, Bastos MG: Cognitive decline, depression and quality of life in patients at different stages of chronic kidney disease. J Bras Nefrol 2010;32:242-248.
  11. Cukor D, Fruchter Y, Ver Halen N, Naidoo S, Patel A, Saggi SJ: A preliminary investigation of depression and kidney functioning in patients with chronic kidney disease. Nephron Clin Pract 2012;122:139-145.
  12. Hedayati SS, Minhajuddin AT, Toto RD, Morris DW, Rush AJ: Prevalence of major depressive episode in CKD. Am J Kidney Dis 2009;54:424-432.
  13. Hedayati SS, Finkelstein FO: Epidemiology, diagnosis, and management of depression in patients with CKD. Am J Kidney Dis 2009;54:741-752.
  14. Odden MC, Whooley MA, Shlipak MG: Depression, stress, and quality of life in persons with chronic kidney disease: the Heart and Soul Study. Nephron Clin Pract 2006;103:c1-c7.
  15. Taraz M, Taraz S, Dashti-Khavidaki S: Association between depression and inflammatory/anti-inflammatory cytokines in chronic kidney disease and end-stage renal disease patients: a review of literature. Hemodial Int 2015;19:11-22.
  16. Uglešić B, Ljutić D, Lasić D, Jeličić I, Višić V, Glavina T, Šundov Ž, Puljiz Ž, Cvitanović MŽ, Meter A: Depression and serum interleukin-6 levels in patients on dialysis. Psychiatr Danub 2015;27:168-173.
  17. Ricardo AC, Fischer MJ, Peck A, Turyk M, Lash JP: Depressive symptoms and chronic kidney disease: results from the National Health and Nutrition Examination Survey (NHANES) 2005-2006. Int Urol Nephrol 2010;42:1063-1068.
  18. NHANES - NHANES 2011-2012 Overview. http://www.cdc.gov/nchs/nhanes/nhanes2011-2012/overview_g.htm (cited October 16, 2015).
  19. NHANES - Survey Methods and Analytic Guidelines. http://www.cdc.gov/nchs/nhanes/survey_methods.htm (cited October 16, 2015).
  20. NHANES - NHANES 2011-2012 - Lab Methods. http://www.cdc.gov/nchs/nhanes/nhanes2011-2012/lab_methods_11_12.htm (cited October 16, 2015).
  21. Moriarty AS, Gilbody S, McMillan D, Manea L: Screening and case finding for major depressive disorder using the Patient Health Questionnaire (PHQ-9): a meta-analysis. Gen Hosp Psychiatry 2015;37:567-576.
  22. Moriarty DG, Kobau R, Zack MM, Zahran HS: Tracking healthy days - a window on the health of older adults. Prev Chronic Dis 2005;2:A16.
  23. NHANES 2011-2012: Current Health Status Data Documentation, Codebook, and Frequencies. http://wwwn.cdc.gov/Nchs/Nhanes/2011-2012/HSQ_G.htm (cited November 11, 2015).
  24. Watnick S, Wang PL, Demadura T, Ganzini L: Validation of 2 depression screening tools in dialysis patients. Am J Kidney Dis 2005;46:919-924.
  25. Hedayati SS, Minhajuddin AT, Toto RD, Morris DW, Rush AJ: Validation of depression screening scales in patients with CKD. Am J Kidney Dis 2009;54:433-439.
  26. Murphy D, McCulloch CE, Lin F, Banerjee T, Bragg-Gresham JL, Eberhardt MS, Morgenstern H, Pavkov ME, Saran R, Powe NR, Hsu CY; Centers for Disease Control and Prevention Chronic Kidney Disease Surveillance Team: Trends in prevalence of chronic kidney disease in the United States. Ann Intern Med 2016;165:473-481.
  27. Pratt LA, Brody DJ: Depression in the U.S. household population, 2009-2012. NCHS Data Brief 2014;172:1-8.
  28. Shirazian S, Diep R, Jacobson AM, Grant CD, Mattana J, Calixte R: Awareness of chronic kidney disease and depressive symptoms: National Health and Nutrition Examination Surveys 2005-2010. Am J Nephrol 2016;44:1-10.

Article / Publication Details

First-Page Preview
Abstract of Clinical Practice: Original Paper

Received: August 23, 2016
Accepted: January 04, 2017
Published online: March 02, 2017
Issue release date: June 2017

Number of Print Pages: 9
Number of Figures: 2
Number of Tables: 3

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: https://www.karger.com/NEF


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