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Original Article

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Economic Evaluation of Intensive Inpatient Treatments for Severely Obese Children and Adolescents

Makkes S.a · van Dongen J.M.a · Renders C.M.a · van der Baan-Slootweg O.H.b · Seidell J.C.a · Bosmans J.E.a

Author affiliations

aDepartment of Health Sciences and the EMGO Institute for Health and Care Research, VU University Amsterdam, Amsterdam, The Netherlands; bMerem Childhood Obesity Center, Heideheuvel, Hilversum, The Netherlands

Corresponding Author

Prof. Dr. Jacob C Seidell

Department of Health Sciences, Faculty of Earth and Life Sciences

VU University Amsterdam

De Boelelaan 1085, 1081 HV Amsterdam, the Netherlands


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Obes Facts 2017;10:458-472

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Background: Considering the large economic consequences of severe childhood obesity for the society, we aimed to conduct an economic evaluation comparing two intensive 1-year lifestyle treatments with varying inpatient periods for severely obese children and adolescents with regard to standard deviation score BMI (SDS-BMI) and quality-adjusted life years (QALYs). Methods: An economic evaluation from a societal perspective accompanying a randomized controlled trial with a 24-month follow-up. 80 participants (8-19 years) with severe obesity were included. Participants received an intensive 1-year lifestyle treatment with an inpatient period of 2 months (short-stay group) or 6 months (long-stay group). Data were collected at baseline, 6, 12 ,and 24 months and included SDS-BMI and QALYs. Results: SDS-BMI decreased in the first 6 months of treatment, stabilized in the second 6 months, and increased during the 2nd year in both groups. After 24 months, SDS-BMI was similar in both groups, but remained lower than baseline values (mean difference -0.24, 95% CI -0.42; -0.06). There was no difference in QALYs between the groups after 24 months. For SDS-BMI, the probability of the short-stay treatment being cost-effective in comparison with the long-stay treatment was 1 at a willingness-to-pay of 0 EUR/unit of effect, which slowly decreased to 0.54 for larger willingness-to-pay values. Conclusions: Based on the results of this study, the short-stay treatment is considered to be more cost-effective from the societal perspective in comparison with the long-stay treatment. Future research should provide insight in whether the short-stay treatment is cost-effective in comparison with usual care.

© 2017 The Author(s) Published by S. Karger GmbH, Freiburg


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Article / Publication Details

First-Page Preview
Abstract of Original Article

Received: July 27, 2016
Accepted: January 25, 2017
Published online: October 07, 2017
Issue release date: October 2017

Number of Print Pages: 15
Number of Figures: 4
Number of Tables: 5

ISSN: 1662-4025 (Print)
eISSN: 1662-4033 (Online)

For additional information: https://www.karger.com/OFA

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