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Clinical Practice: Original Paper

Measuring Fatigue Using the Multidimensional Fatigue Inventory-20: A Questionable Factor Structure in Haemodialysis Patients

Chilcot J.a · Guirguis A.b, c · Friedli K.c · Almond M.d · Davenport A.e · Day C.f · Wellsted D.c · Farrington K.b, g

Author affiliations

aInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, bPostgraduate Medical School, and cCentre for Lifespan and Chronic Illness Research, University of Hertfordshire, Cambridge, dSouthend University Hospital NHS Foundation Trust, Southend, eUCL Centre for Nephrology, Royal Free Hospital NHS Foundation Trust, London, fDepartment of Renal Medicine, University Hospitals Birmingham NHS Foundation Trust, Birmingham, and gLister Hospital, East and North Hertfordshire NHS Trust, Stevenage, UK

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Nephron 2017;136:121-126

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Article / Publication Details

First-Page Preview
Abstract of Clinical Practice: Original Paper

Received: December 14, 2016
Accepted: February 02, 2017
Published online: February 28, 2017
Issue release date: June 2017

Number of Print Pages: 6
Number of Figures: 1
Number of Tables: 2

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: https://www.karger.com/NEF

Abstract

Background/Aims: Fatigue is recognised as a common and burdensome symptom among dialysis patients. A growing body of research is devoted to understanding fatigue in advanced kidney disease, yet its measurement is challenging within this context. Our aim was to evaluate the factor structure underlying the multidimensional fatigue inventory (MFI-20) and to examine its associations with clinical factors and mood. Methods: Data was evaluated for confirmatory factor analysis (CFA) from the screening phase of a multicentre randomised placebo-controlled trial of sertraline in haemodialysis (HD) patients. Four hundred seventy patients completed the MFI-20, which purports to measure 5 components of fatigue (general fatigue, mental fatigue, physical fatigue, reduced motivation and reduced activity). CFA models were evaluated in MPlus 7.3 using the robust maximum likelihood (MLR) estimation. Results: The evaluation of the original 5 factors revealed low internal reliability for the general factor and reduced activity, and high intercorrelations between all sum scores. CFA revealed poor model fit for the original 5-factor MFI-20 model (confirmatory fit index = 0.738; Tucker-Lewis index = 0.689; root mean squared error of approximation = 0.101). Alternative models, including 1, 3 and bi-factor models all demonstrated poor fit to the data. No reliable factor model was confirmed prohibiting the examination of factors associated with fatigue. Conclusions: We were not able to confirm the factor structure of the MFI-20 in a large sample of HD patients. Certain items may lack suitable face validity in this context.

© 2017 S. Karger AG, Basel


References

  1. Artom M, Moss-Morris R, Caskey F, Chilcot J: Fatigue in advanced kidney disease. Kidney Int 2014;86:497-505.
  2. Bossola M, Di Stasio E, Antocicco M, Panico L, Pepe G, Tazza L: Fatigue is associated with increased risk of mortality in patients on chronic hemodialysis. Nephron 2015;130:113-118.
  3. Chilcot J, Moss-Morris R, Artom M, Harden L, Picariello F, Hughes H, Bates S, Macdougall IC: Psychosocial and clinical correlates of fatigue in haemodialysis patients: the importance of patients' illness cognitions and behaviours. Int J Behav Med 2016;23:271-281.
  4. Bossola M, Vulpio C, Tazza L: Fatigue in chronic dialysis patients. Semin Dial 2011;24:550-555.
  5. Picariello F, Moss-Morris R, Macdougall IC, Chilcot J: The role of psychological factors in fatigue among end-stage kidney disease patients: a critical review. Clin Kidney J 2017;10:79-88.
  6. Chilcot J, Norton S, Kelly ME, Moss-Morris R: The chalder fatigue questionnaire is a valid and reliable measure of perceived fatigue severity in multiple sclerosis. Mult Scler 2016;22:677-684.
  7. Michielsen HJ, De Vries J, Van Heck GL, Van de Vijver FJR, Sijtsma K: Examination of the dimensionality of fatigue. Eur J Psychol Assess 2004;20:39-48.
  8. Picariello F, Moss-Morris R, Macdougall IC, Chilcot J: Measuring fatigue in haemodialysis patients: the factor structure of the Chalder Fatigue Questionnaire (CFQ). J Psychosom Res 2016;84:81-83.
  9. McCann K, Boore JR: Fatigue in persons with renal failure who require maintenance haemodialysis. J Adv Nurs 2000;32:1132-1142.
  10. O'Sullivan D, McCarthy G: An exploration of the relationship between fatigue and physical functioning in patients with end stage renal disease receiving haemodialysis. J Clin Nurs 2007;16:276-284.
  11. Smets EM, Garssen B, Bonke B, De Haes JC: The multidimensional fatigue inventory (MFI) psychometric qualities of an instrument to assess fatigue. J Psychosom Res 1995;39:315-325.
  12. Chandel P, Sultan A, Khan KA, Choudhary V, Parganiha A: Validation of the Hindi version of the multidimensional fatigue inventory-20 (MFI-20) in Indian cancer patients. Support Care Cancer 2015;23:2957-2964.
  13. Elbers RG, van Wegen EE, Verhoef J, Kwakkel G: Reliability and structural validity of the multidimensional fatigue inventory (MFI) in patients with idiopathic Parkinson's disease. Parkinsonism Relat Disord 2012;18:532-536.
  14. Baptista RL, Biasoli I, Scheliga A, Soares A, Brabo E, Morais JC, Werneck GL, Spector N: Psychometric properties of the multidimensional fatigue inventory in Brazilian Hodgkin's lymphoma survivors. J Pain Symptom Manage 2012;44:908-915.
  15. Lin JM, Brimmer DJ, Maloney EM, Nyarko E, Belue R, Reeves WC: Further validation of the multidimensional fatigue inventory in a US adult population sample. Popul Health Metr 2009;7:18.
  16. Friedli K, Almond M, Day C, Chilcot J, Gane Mda S, Davenport A, Guirguis A, Fineberg N, Spencer B, Wellsted D, Farrington K: A study of sertraline in dialysis (ASSertID): a protocol for a pilot randomised controlled trial of drug treatment for depression in patients undergoing haemodialysis. BMC Nephrol 2015;16:172.
  17. Friedli K, Guirguis A, Almond M, Day C, Chilcot J, Gane MDS, Davenport A, Fineberg N, Spencer B, Wellsted D, Farrington K: Sertraline versus placebo in patients with major depressive disorder and undergoing haemodialysis (ASSertID): a randomised, controlled feasibility trial. Clin J Am Soc Nephrol 2017;12:280-286.
  18. Beck AT, Steer RA, Brown GK: Beck Depression Inventory - 2nd Edition Manual. San Antonio, The Psychological Corporation, 1996.
  19. Spitzer RL, Kroenke K, Williams JB: Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary care evaluation of mental disorders. Patient Health Questionnaire. JAMA 1999;282:1737-1744.
  20. Chilcot J, Wellsted D, Farrington K: Screening for depression while patients dialyse: an evaluation. Nephrol Dial Transplant 2008;23:2653-2659.
  21. Chilcot J, Norton S, Wellsted D, Almond M, Davenport A, Farrington K: A confirmatory factor analysis of the Beck Depression Inventory-II in end-stage renal disease patients. J Psychosom Res 2011;71:148-153.
  22. Watnick S, Wang PL, Demadura T, Ganzini L: Validation of 2 depression screening tools in dialysis patients. Am J Kidney Dis 2005;46:919-924.
  23. Ullman JB: Structural equation modeling: reviewing the basics and moving forward. J Pers Assess 2006;87:35-50.
  24. Hu L, Bentler PM: Cutoff criteria for fit indexes in covariance structure analysis: conventional criteria versus new alternatives. Struct Equ Modeling 1999;6:1-55.
  25. Flora DB, Curran PJ: An empirical evaluation of alternative methods of estimation for confirmatory factor analysis with ordinal data. Psychol Methods 2004;9:466-491.
  26. Chilcot J, Wellsted D, Da Silva-Gane M, Farrington K: Depression on dialysis. Nephron Clin Pract 2008;108:c256-c264.
  27. MacNeill SJ, Casula A, Shaw C, Castledine C: UK renal registry 18th annual report: chapter 2 UK renal replacement therapy prevalence in 2014: national and centre-specific analyses. Nephron 2016;132(suppl 1):41-68.
  28. Steenkamp R, Caskey F: UK renal registry 18th annual report: chapter 6 comorbidities and current smoking status amongst patients starting renal replacement therapy in England, Wales and Northern Ireland from 2013 to 2014. Nephron 2016;132(suppl 1):145-154.

Article / Publication Details

First-Page Preview
Abstract of Clinical Practice: Original Paper

Received: December 14, 2016
Accepted: February 02, 2017
Published online: February 28, 2017
Issue release date: June 2017

Number of Print Pages: 6
Number of Figures: 1
Number of Tables: 2

ISSN: 1660-8151 (Print)
eISSN: 2235-3186 (Online)

For additional information: https://www.karger.com/NEF


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