American Journal of Nephrology
Clinical Study
Comparison of Blood Loss with Different High-Flux and High-Efficiency Hemodialysis MembranesOtti T. · Khajehdehi P. · Fawzy A. · Gellens M. · Bastani B.Division of Nephrology, Saint Louis University Health Sciences Center, St. Louis, Mo., USA
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Article / Publication Details
Published online: March 12, 2001
Issue release date: January – February
Number of Print Pages: 4
Number of Figures: 1
Number of Tables: 2
ISSN: 0250-8095 (Print)
eISSN: 1421-9670 (Online)
For additional information: https://www.karger.com/AJN
Abstract
Iron deficiency is a common problem in patients on chronic HD. Earlier studies have shown significant blood loss per HD session. To identify whether the new more biocompatible high-flux or high-efficiency membranes are also responsible for significant blood loss during HD, we quantitated the amount of blood loss associated with 4 commonly used membranes (F-50, F-80, CA-210, and CT-190). The residual blood in each compartment of extracorporeal circuit was quantitated after total lysis of the red blood cells (RBC), hemoglobin assay, and calculation of the RBC volume using the patient’s hemoglobin and hematocrit concentrations just prior to the study. The average residual RBC volume in different membranes was 0.2–0.3 ml. The residual RBC volume in the dialysis lines (arterial or venous) was 0.1–0.2 ml and did not correlate with the residual RBC volume in the dialysis membranes. The residual RBC volume in the whole extracorporeal circuit (HD membrane, arterial and venous lines) ranged from 0.5 to 0.6 ml. It was significantly higher with F-50 vs. CA-210. The residual RBC volume in the dialysis membrane was significantly higher in the F-80 vs. CA-210 and CT-190 dialyzers. There was also significant difference in the residual RBC volume in the arterial lines of F-50 vs. CT-190, and F-50 vs. F-80 dialyzers. Conclusion: Our results demonstrate for the first time that the total RBC loss per HD session is minimal in chronic HD patients.
© 2001 S. Karger AG, Basel
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Article / Publication Details
Published online: March 12, 2001
Issue release date: January – February
Number of Print Pages: 4
Number of Figures: 1
Number of Tables: 2
ISSN: 0250-8095 (Print)
eISSN: 1421-9670 (Online)
For additional information: https://www.karger.com/AJN
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