Enzyme
Original Paper
Effects of Substrate Fatty Acids on Products of Lecithin Hydrolysis and Acyl-CoA-Independent Transacylation with Cholesterol by Aortic Enzyme PreparationsPatelksi J. · Pioruńska-Stolzmann M.Department of General Chemistry, Medical Academy, Poznań, Poland
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Article / Publication Details
Published online: August 11, 2017
Issue release date: 1985
Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0
ISSN: 0013-9432 (Print)
eISSN: 2504-2564 (Online)
For additional information: https://www.karger.com/EZD
Abstract
The acyl composition of substrates and products of enzymatic hydrolysis and transacylation of lecithin with cholesterol in the arterial wall was investigated. Saturated acyl residues predominated in lysolecithin and unsaturated ones in acids released by hydrolysis of egg lecithin. In the reaction system with cholesterol, saturated acyls predominated in both lysolecithin and acids released whereas unsaturated ones were more abundant in newly formed acylcholesterols. Mainly unsaturated acyls were present in the hydrolysis products from soybean lecithin in the reaction systems with and without cholesterol. For acylcholesterols formed in the presence of either lecithin, the percent values are in the numerical order of C(18:2) > C(18:2) > C(16:0) > C(18:0) It is concluded that acyl preferences and interactions in the enzyme-catalyzed reactions studied may contribute to the different accumulation and removal of the compounds involved from the artery.
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Article / Publication Details
Published online: August 11, 2017
Issue release date: 1985
Number of Print Pages: 3
Number of Figures: 0
Number of Tables: 0
ISSN: 0013-9432 (Print)
eISSN: 2504-2564 (Online)
For additional information: https://www.karger.com/EZD
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