Login to MyKarger

New to MyKarger? Click here to sign up.



Login with Facebook

Forgot your password?

Authors, Editors, Reviewers

For Manuscript Submission, Check or Review Login please go to Submission Websites List.

Submission Websites List

Institutional Login
(Shibboleth or Open Athens)

For the academic login, please select your country in the dropdown list. You will be redirected to verify your credentials.

Manifestations of Oxidant Stress in Uremia

Himmelfarb J. · McMonagle E.

Author affiliations

Division of Nephrology, Maine Medical Center, Portland, Me., USA

Related Articles for ""

Blood Purif 2001;19:200–205

Do you have an account?

Login Information





Contact Information










I have read the Karger Terms and Conditions and agree.



Login Information





Contact Information










I have read the Karger Terms and Conditions and agree.



To view the fulltext, please log in

To view the pdf, please log in

Buy

  • FullText & PDF
  • Unlimited re-access via MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

CHF 38.00 *
EUR 35.00 *
USD 39.00 *

Select

KAB

Buy a Karger Article Bundle (KAB) and profit from a discount!

If you would like to redeem your KAB credit, please log in.


Save over 20% compared to the individual article price.
Learn more

Rent/Cloud

  • Rent for 48h to view
  • Buy Cloud Access for unlimited viewing via different devices
  • Synchronizing in the ReadCube Cloud
  • Printing and saving restrictions apply

Rental: USD 8.50
Cloud: USD 20.00


Select

Subscribe

  • Access to all articles of the subscribed year(s) guaranteed for 5 years
  • Unlimited re-access via Subscriber Login or MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

Subcription rates


Select

* The final prices may differ from the prices shown due to specifics of VAT rules.

Article / Publication Details

Published online: December 28, 2000
Issue release date: 2001

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0

ISSN: 0253-5068 (Print)
eISSN: 1421-9735 (Online)

For additional information: https://www.karger.com/BPU


First-Page Preview
Abstract of Paper

References

  1. Halliwell B, Gutteridge JMC, Cross CE: Free radicals, antioxidants, and human disease: Where are we now? J Lab Clin Med 1992;119:598–620.
  2. Cross CE, Halliwell B, Borish ET, Pryor WA, Ames BN, Saul RL, McCord JM, Harman D: Oxygen radicals and human disease. Ann Intern Med 1987;107:526–545.
  3. Weiss SJ: Tissue destruction by neutrophils. N Engl J Med 1989;320:365–376.
  4. Miller RA, Britigan BE: The formation and biologic significance of phagocyte-derived oxidants. J Invest Med 1995;43:39–49.
  5. Heinecke JW: Mechanisms of oxidative damage by myeloperoxidase in atherosclerosis and other inflammatory disorders. J Lab Clin Med 1999;133:321–325.
  6. Steinberg D: Role of oxidized LDL and antioxidants in atherosclerosis. Adv Exp Med Biol 1995;369:39–48.
  7. Davies MJ, Fu S, Wang H, Dean RT: Stable markers of oxidant damage to proteins and their application in the study of human disease. Free Radic Biol Med 1999;27:1151–1163.
  8. Tetta C, Biasioli S, Schiavon R, Inguaggiato P, David S, Panichi V, Wratten ML: An overview of haemodialysis and oxidative stress. Blood Purif 1999;17:118–126.
  9. Stadtman ER: Metal ion-catalyzed oxidation of proteins: Biochemical mechanism and biological consequences. Free Radic Biol Med 1990;9:315–325.
  10. Lee Y, Shacter E: Role of carbohydrates in oxidative modification of fibrinogen and other plasma proteins. Arch Biochem Biophys 1995;321:175–181.
  11. Stadtman ER: Role of oxidized amino acids in protein breakdown and stability. Methods Enzymol 1995;258:379–393.
  12. Dean RT, Fu S, Stocker R, Davies MJ: Biochemistry and pathology of radical-mediated protein oxidation. Biochem J 1997;324:1–18.
  13. Heinecke JW: Mass spectrometric quantification of amino acid oxidation products in protein: Insights into pathways that promote LDL oxidation in the human artery wall. FASEB J 1999;13:1113–1120.
  14. Domigan NM, Charlton TS, Duncan MW, Winterbourn CC, Kettle AJ: Chlorination of tyrosyl residues in peptides by myeloperoxidase and human neutrophils. J Biol Chem 1995;270:16542–16548.
  15. Hazen SL, Hsu FF, Mueller DM, Crowley JR, Heinecke JW: Human neutrophils employ chlorine gas as an oxidant during phagocytosis. J Clin Invest 1996;98:1283–1289.
    External Resources
  16. Hazen SL, Heinecke JW: 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. J Clin Invest 1997;99:2075–2081.
  17. O’Neill CA, Halliwell B, van der Vliet A, Davis PA, Packer L, Tritschler H, Strohman WJ, Rieland T, Cross CE, Reznick AZ: Aldehyde-induced protein modifications in human plasma: Protection by glutathione and dihydrolipoic acid. J Lab Clin Med 1994;124:359–370.
  18. Anderson MM, Hazen SL, Hsu FF, Heinecke JW: Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal and acrolein. J Clin Invest 1997;99:424–432.
    External Resources
  19. Hazen SL, Gaut JP, Hsu FF, Crowley JR, d’Avignon A, Heinecke JW: p-Hydroxyphenylacetaldehyde, the major product of L-tyrosine oxidation by the myeloperoxidase-H2O2-chloride system of phagocytes, covalently modifies ε-amino groups of protein lysine residues. J Biol Chem 1997;272:16990–16996.
  20. Stenvinkel P, Heimburger O, Paultre F, Diczfalusy U, Wang T, Berglund L, Jogestrand T: Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal failure. Kidney Int 1999;51:1899–1911.
  21. Ward RA, McLeish KR: Polymorphonuclear leukocyte oxidative burst is enhanced in patients with chronic renal insufficiency. J Am Soc Nephrol 1995;5:1697–1702.
  22. Ward RA: Phagocytic cell function as an index of biocompatibility. Nephrol Dial Transplant 1994;9:46–56.
    External Resources
  23. Cheung AK: Biocompatibility of dialysis membranes. J Am Soc Nephrol 1990;1:150–161.
  24. Ellman GL: Tissue sulfhydryl groups. Arch Biochem Biophys 1959;82:70–77.
  25. Hu ML, Louie S, Cross CE, Motchnik P, Halliwell B: Antioxidant protection against hypochlorous acid in human plasma. J Lab Clin Med 1993;121:257–262.
  26. Bohlen P, Stein S, Dairman W, Udenfriend S: Fluorometric assay of proteins in the nanogram range. Arch Biochem Biophys 1973;155:213–220.
    External Resources
  27. Davies KJA, Delsignore ME, Lin SW: Protein damage and degradation by oxygen radicals. II. Modification of amino acids. J Biol Chem 1987;262:9902–9907.
  28. Arnhold J, Hammerschmidt S, Wagner M, Meuller S, Arnold K, Grimm E: On the action of hypochlorite in human serum albumin. Biomed Biochim Acta 1990;49:991–997.
  29. Levine RL, Garland D, Oliver CN, Amici A, Climent I, Anke GL, Bong-Whan A, Shaltiel S, Stadtman ER: Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 1990;189:464–478.
  30. Hu ML, Tappel A: Potentiation of oxidative damage to proteins by ultraviolet-A and protection by antioxidants. Photochem Photobiol 1992;56:357–363.
    External Resources
  31. Reznick AZ, Cross CE, Hu ML, Suzuki YJ, Khwarja S, Safadi A, Motchnik PA, Packer L, Halliwell B: Modification of plasma proteins by cigarette smoke as measured by protein carbonyl formation. Biochem J 1992;286:607–611.
  32. Himmelfarb J, McMonagle E, McMenamin E: Plasma protein thiol oxidation and carbonyl formation in chronic renal failure. Kidney Int (accepted).

Article / Publication Details

Published online: December 28, 2000
Issue release date: 2001

Number of Print Pages: 6
Number of Figures: 0
Number of Tables: 0

ISSN: 0253-5068 (Print)
eISSN: 1421-9735 (Online)

For additional information: https://www.karger.com/BPU


Copyright / Drug Dosage / Disclaimer

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.