Login to MyKarger

New to MyKarger? Click here to sign up.



Login with Facebook

Forgot your password?

Authors, Editors, Reviewers

For Manuscript Submission, Check or Review Login please go to Submission Websites List.

Submission Websites List

Institutional Login
(Shibboleth or Open Athens)

For the academic login, please select your country in the dropdown list. You will be redirected to verify your credentials.

Original Paper

Preventive and Therapeutic Proximal Sealing: A 3.5-Year Randomized Controlled Clinical Trial Follow-Up

Basili C.P.a · Emilson C.G.b · Corvalan G.C.a · Moran M.P.a · Torres C.a · Quiroz M.D.a · Gomez S.S.a

Author affiliations

aDepartment of Preventive Dentistry, Facultad de Odontología, Valparaiso University, Valparaíso, Chile; bInstitute of Odontology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden

Related Articles for ""

Caries Res 2017;51:387-393

Do you have an account?

Login Information





Contact Information












By signing up for MyKarger you will automatically participate in our year-End raffle.
If you Then Do Not wish To participate, please uncheck the following box.

Yes, I wish To participate In the year-End raffle And Get the chance To win some Of our most interesting books, And other attractive prizes.


I have read the Karger Terms and Conditions and agree.



Login Information





Contact Information












By signing up for MyKarger you will automatically participate in our year-End raffle.
If you Then Do Not wish To participate, please uncheck the following box.

Yes, I wish To participate In the year-End raffle And Get the chance To win some Of our most interesting books, And other attractive prizes.


I have read the Karger Terms and Conditions and agree.



To view the fulltext, please log in

To view the pdf, please log in

Buy

  • FullText & PDF
  • Unlimited re-access via MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

CHF 38.00 *
EUR 35.00 *
USD 39.00 *

Select

KAB

Buy a Karger Article Bundle (KAB) and profit from a discount!

If you would like to redeem your KAB credit, please log in.


Save over 20% compared to the individual article price.
Learn more

Rent/Cloud

  • Rent for 48h to view
  • Buy Cloud Access for unlimited viewing via different devices
  • Synchronizing in the ReadCube Cloud
  • Printing and saving restrictions apply

Rental: USD 8.50
Cloud: USD 20.00


Select

Subscribe

  • Access to all articles of the subscribed year(s) guaranteed for 5 years
  • Unlimited re-access via Subscriber Login or MyKarger
  • Unrestricted printing, no saving restrictions for personal use
read more

Subcription rates


Select

* The final prices may differ from the prices shown due to specifics of VAT rules.

Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: September 01, 2016
Accepted: March 07, 2017
Published online: June 16, 2017
Issue release date: August 2017

Number of Print Pages: 7
Number of Figures: 1
Number of Tables: 2

ISSN: 0008-6568 (Print)
eISSN: 1421-976X (Online)

For additional information: https://www.karger.com/CRE

Abstract

Objective: The aim of this split-mouth, randomized controlled clinical trial was to evaluate the efficacy of proximal sealing for avoiding the development of new caries lesions or arresting incipient caries lesions on the mesial surface of first permanent molars (6m) abutting lesions on the distal surface of second primary molars (05d) in children at high caries risk. Methods: A total of 61 children 8-10 years old were selected based on the caries status of the proximal sites of 05d and 6m. Children with caries on 05d and caries-free 6m were placed in the preventive sealing group and children with caries on both 05d and 6m in the therapeutic group. The children in each group had one 6m surface pair and in each pair one 6m surface was randomly allocated to receive a preventive or therapeutic sealing. Using a split-mouth design, the other 6m surface in the pair served as control. Results: After 3.5 years, standardized follow-up radiographs were obtained for the 45 children who remained. In the preventive sealing group, 4 out of 30 (13.3%) sealed and 16 out of 30 (53.3%) unsealed sound 6m surfaces had developed new caries lesions (p = 0.004, McNemar test). In the therapeutic sealing group, the progression of the carious lesions on 6m was observed in 3 out of 15 sealed (20.0%) and 8 out of 15 (53.3%) unsealed caries control surfaces (p = 0.06). Conclusions: Preventive sealing on sound 6m surfaces abutting 05d lesions in children at high caries risk efficaciously prevents the development of caries lesions. Therapeutically sealing active non-cavitated caries lesions reduces the progression.

© 2017 S. Karger AG, Basel


References

  1. Ammari MM, Soviero VM, da Silva Fidalgo TK, Lenzi M, Ferreira DM, Mattos CT, de Souza IP, Maia LC: Is non-cavitated proximal lesion sealing an effective method for caries control in primary and permanent teeth? A systematic review and meta-analysis. J Dent 2014;42:1217-1227.
  2. Bratthall D, Hänsel Petersson G: Cariogram - a multifactorial risk assessment model for a multifactorial disease. Community Dent Oral Epidemiol 2005;33:256-264.
  3. Cook RJ, Sackett DL: The number needed to treat: a clinically useful measure of treatment effect. BMJ 1995;310:452-454.
  4. Dorri M, Dunne SM, Walsh T, Schwendicke F: Micro-invasive interventions for managing proximal dental decay in primary and permanent teeth. Cochrane Database Syst Rev 2015;11:CD010431.
  5. Gomez SS, Basili CP, Emilson CG: A 2-year clinical evaluation of sealed noncavitated approximal posterior carious lesions in adolescents. Clin Oral Investig 2005;9:239-243.
  6. Gomez SS, Onetto JE, Uribe SA, Emilson CG: Therapeutic seal of approximal incipient noncavitated carious lesions: technique and case reports. Quintessence Int 2007;38:e99-e105.
    External Resources
  7. Gomez SS, Emilson CG, Corvalan GC, Quiroz MD, Moran MP: Efficacy of sealing the mesial surfaces of first permanent molars with respect to the status of the distal surfaces of the second primary molars in children at high caries-risk. Eur Arch Paediatr Dent 2014;15:65-73.
  8. Griffin SO, Oong E, Kohn W, Vidakovic B, Gooch BF; CDC Dental Sealant Systematic Review Work Group, Bader J, Clarkson J, Fontana MR, Meyer DM, Rozier RG, Weintraub JA, Zero DT: The effectiveness of sealants in managing caries lesions. J Dent Res 2008;87:169-174.
  9. Leroy R, Bogaerts K, Lesaffre E, Declerck D: Effect of caries experience in primary molars on cavity formation in the adjacent permanent first molar. Caries Res 2005;39:342-349.
  10. Martignon S, Ekstrand KR, Gomez J, Lara JS, Cortes A: Infiltrating/sealing proximal caries lesions: a 3-year randomized clinical trial. J Dent Res 2012;91:288-292.
  11. Mejàre I, Stenlund H, Julihn A, Larsson I, Permert L: Influence of approximal caries in primary molars on caries rate for the mesial surface of the first permanent molar in Swedish children from 6 to 12 years of age. Caries Res 2001;35:178-185.
    External Resources
  12. Mejàre I, Kidd EAM: Radiography for caries diagnosis; in Fejerskov O, Kidd E (eds): Dental Caries: The Disease and Clinical Management, ed 2. Oxford, Blackwell Munksgaard Ltd, 2008, pp 69-88.
  13. Meyer-Lueckel H, Balbach A, Schikowsky C, Bitter K, et al: Pragmatic RCT on the efficacy of proximal caries infiltration. J Dent Res 2016;95:531-536.
  14. Nyvad B, Fejerskov O, Baelum V: Visual-tactile caries diagnosis; in Fejerskov O, Kidd E (eds): Dental Caries. The Disease and Its Clinical Management, ed 2. Oxford, Blackwell Munksgaard Ltd, 2008, pp 49-68.
  15. Simonsen RJ, Neal RC: A review of the clinical application and performance of pit and fissure sealants. Aust Dent J 2011;56(suppl 1):45-58.
  16. Skeie MS, Raadal M, Strand GV, Espelid I: The relationship between caries in the primary dentition at 5 years of age and permanent dentition at 10 years of age - a longitudinal study. Int J Paediatr Dent 2006;16:152-160.
  17. Splieth CH, Ekstrand KR, Alkilzy M, Clarkson J, Meyer-Lueckel H, Martignon S, Paris S, Pitts NB, Ricketts DN, Van Loveren C: Sealants in dentistry: outcomes of the ORCA Saturday afternoon symposium 2007. Caries Res 2010;44:3-13.
  18. Schwendicke F, Meyer-Lueckel H, Stolpe M, Dörfer CE, Paris S: Costs and effectiveness of treatment alternatives for proximal caries lesions. PLos One 2014;9:e86992.
  19. Schwendicke F, Jäger AM, Paris S, Hsu LY, Tu YK: Treating pit-and-fissure caries: a systematic review and network meta-analysis. J Dent Res 2015;94:522-533.
  20. World Health Organization: Oral Health Surveys - Basic Methods, ed 4. Geneva, World Health Organization, 1997.
  21. Vanderas AP, Kavvadia K, Papagiannoulis L: Development of caries in permanent first molars adjacent to primary second molars with interproximal caries: four-year prospective radiographic study. Pediatr Dent 2004;26:362-368.
    External Resources
  22. Zero DT, Fontana M, Martínez-Mier EA, Ferreira-Zandoná A, Ando M, González-Cabezas C, Bayne S: The biology, prevention, diagnosis and treatment of dental caries: scientific advances in the United States. J Am Dent Assoc 2009;140(suppl 1):25S-34S.

Article / Publication Details

First-Page Preview
Abstract of Original Paper

Received: September 01, 2016
Accepted: March 07, 2017
Published online: June 16, 2017
Issue release date: August 2017

Number of Print Pages: 7
Number of Figures: 1
Number of Tables: 2

ISSN: 0008-6568 (Print)
eISSN: 1421-976X (Online)

For additional information: https://www.karger.com/CRE


Copyright / Drug Dosage / Disclaimer

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.